Antitumor Amino-Substituted Pyridopyrroloisoquinolines and Pyridocarbazole Derivatives: Synthesis and Evaluation of Compoudns Resulting from New Side Chain and Heterocycle Modifications

DOI: 10.1021/jm00356a012

Source and publish data:

Journal of Medicinal Chemistry p. 181 - 185 (1983)

Update date:2022-08-04

Topics:

Authors:

Rivalle, Christian

Wendling, Francoise

Tambourin, Pierre

Lhoste, Jean-Marc

Bisagni, Emile

Chermann, Jean-Claude

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Article abstract of DOI:10.1021/jm00356a012

New modifications of 10-<<3-(diethylamino)propyl>amino>-6-methyl-5H-pyrido<3',4':4,5>pyrrolo<2,3-g>isoquinoline (1b) and 1-<<3-(diethylamino)propyl>amino>-9-methoxy-5,11-dimethyl-6H-pyrido<4,3-b>carbazole (4b), which display important antitumor properties

Full text of DOI:10.1021/jm00356a012

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Product name:3-[(6-Methyl-5H-pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinolin-10-yl)amino]-1,2-propanediol

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