FRIEDEL-CRAFTS REACTION OF 3,6-DIHYDRO-4-METHYL-2H-PYRAN WITH PHENOLS. A CONVENIENT SYNTHESIS OF A KEY INTERMEDIATE OF ALPHA-TOCOPHEROL

DOI: 10.1246/cl.1985.1399

Source and publish data:

Chemistry Letters p. 1399 - 1400 (1985)

Update date:2022-08-05

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Authors:

Fujita, Yoshiji

Shiono, Manzo

Ejiri, Katsushi

Saita, Kazumi

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Article abstract of DOI:10.1246/cl.1985.1399

The Friedel-Crafts reaction of 3,6-dihydro-4-methyl-2H-pyran with 2,3,5-trimethylhydroquinone afforded 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-ethanol in good yield.

Full text of DOI:10.1246/cl.1985.1399

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