ENANTIOCONTROLLED SYNTHESIS OF (S)-3-SUBSTITUTED CYCLOALKANONES FROM (S)-2-(p-TOLYLSULFINYL)-2-CYCLOALKENONES AND DIORGANOMAGNESIUM REAGENTS.

Article abstract of DOI:10.1016/S0040-4039(00)99888-5

By appropriate choice of reaction conditions, the same enantiomerically pure (S)-(+)-2-(p-tolylsulfinyl)cycloalkenone can be converted into either an (R)- or an (S)-3-substituted cycloalkanone in good to excellent enantiomeric purity.