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regioselectivity. This method could also be utilized in the late-
stage functionalization of bioactive compounds and amino
acids. Further applications of this interrupted click reaction
strategy in organic synthesis and medicinal chemistry are
underway in our laboratory.
ASSOCIATED CONTENT
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S
* Supporting Information
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The Supporting Information is available free of charge on the
Experimental details and spectral data for new com-
X-ray data for compound 4a (CIF)
AUTHOR INFORMATION
Corresponding Authors
■
Notes
The authors declare no competing financial interest.
ACKNOWLEDGMENTS
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Potukuchi, H. K.; Novak, P.; Buttner, L. Org. Lett. 2010, 12, 2056.
̈
We are grateful for financial support from the Natural Science
Foundation of China and Shandong province (Nos. 21572118,
21372144, and JQ201505), the fundamental research and
subject construction funds (Nos. 2014JC008, 104.205.2.5), and
the Zhong-Ying scholar award of Shandong University.
(p) Chuprakov, S.; Chernyak, N.; Dudnik, A. S.; Gevorgyan, V. Org.
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