Chemistry of Heterocyclic Compounds p. 456 - 461 (1990)
Update date:2022-08-10
Topics:
Iovel', I. G.
Yansone, I. Ya.
Gol'dberg, Yu. Sh.
Shimanskaya, M. V.
The vapor-phase oxidation of 2,5-dimethylpyrazine with oxygen on vanadium-molybdenum oxide catalysts modified with silver oxide gives 5-methyl-2-formylpyrazine and 2,5-diformylpyrazine in 37percent and 35percent yields, respectively.Pyrazine-2,5-dicarboxylic acid was obtained in 53percent yield by the liquid-phase oxidation of 2,5-dimethylpyrazine with oxygen in the presence of a strong base and an interphase catalyst.
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