Helvetica Chimica Acta p. 404 - 409 (1986)
Update date:2022-08-28
Topics:
Fizet, Christian
The optical resolution of (RS)-pantolactone (1) is carried out through formation of diastereomeric amides.These are separated by a single hot washing with CH2Cl2 or CHCl3.The used asymmetric amine, (1R)-3-endo-aminoborneol (4), is readily accessible and can be recovered almost quantitatively after resolution.
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