Tetrahedron Letters p. 5741 - 5744 (1997)
Update date:2022-08-28
Topics:
Cacciola, Joseph
Alexander, Richard S.
Fevig, John M.
Stouten, Pieter F.W.
We describe a novel route for the preparation of substituted α-ketoamides of lysine. These compounds, due to the presence of an electrophilic carbonyl, display submicromolar activity toward the enzyme thrombin.
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