2444-46-4

Basic information

• Product Name: Nonivamide
• Synonyms: Nonivamide(Synthetic Capsaicin);N-((Hydroxy-3-methoxyphenyl)methyl)4-nonanamide;N-Nonanoyl vanillylamide;Nonanamide, N-((4-hydroxy-3-methoxyphenyl)meth;n-((4-hydroxy-3-methoxyphenyl)methyl)-nonanamid;n-[(4-hydroxy-3-methoxyphenyl)methyl]-nonanamid;Nonanoylvanilylamide;nonylicacidvanillylamide(nonivamide)
• CAS NO: 2444-46-4
• Molecular Formula: C₁₇H₂₇NO₃
• Molecular Weight: 293.4
• EINECS: 219-484-1
• Product Categories: Inhibitors;API;INORGANIC & ORGANIC CHEMICALS;Anilines, Aromatic Amines and Nitro Compounds;Plant extract;Herb extract
• Mol File: 2444-46-4.mol
• Article Data: 29

Chemical Properties

• Melting Point: 54°C
• Boiling Point: 492.7 °C at 760 mmHg
• Flash Point: 190°C
• Appearance: white to off-white/powder
• Density: 1,1 g/cm3
• Vapor Pressure: 2.48E-10mmHg at 25°C
• Refractive Index: 1.513
• Storage Temp.: 2-8°C
• Solubility: methanol: 100 mg/mL, clear to slightly hazy
• PKA: 9.76±0.20(Predicted)
• Stability: Stable. Incompatible with strong oxidizing agents.
• BRN: 2144300
• CAS DataBase Reference: Nonivamide(CAS DataBase Reference)
• NIST Chemistry Reference: Nonivamide(2444-46-4)
• EPA Substance Registry System: Nonivamide(2444-46-4)

Safety Data

• Hazard Codes: T,Xi
• Statements: 25-36/37/38-43
• Safety Statements: 26-45-37/39-36/37
• RIDADR: UN 3462 6.1/PG 2
• WGK Germany: 3
• RTECS: RA5998000
• F: 19
• HazardClass: 6.1
• PackingGroup: II
• Hazardous Substances Data: 2444-46-4(Hazardous Substances Data)

Usage

Description

Nonanoyl-4-hydroxy-3-methoxybenzylamide is odorless with a pungent, burning taste. Synthesized from nonanyl chloride and vanillylamine.

Description

Nonivamide is also called pelargonic acid vanillylamide or PAVA. It is a capsaicinoid. Nonivamide, isolated from peppers, is a naturally occurring analog of capsaicin (sc-3577). Similar to capsaicin, nonivamide can activate the TRPV1 receptor, thus, stimulate the firing rate of dopaminergic neurons in the ventral tegmental area of the brain and to increase the expression of the serotonin receptor gene HTR2A. Nonivamide is with lower TRPV1 binding affinity, thus, a reduced pungency (9 200 000 scoville heat units) compared to capsaicin (16 000 000 scoville heat units). Nonivamide is used in the food production to add a hot sensation to flavoring agents and spice mixtures. It is also used in the sweets and confectionary industries to add hot sensation into products. In pharmaceutical industries, nonivamide is used as a cheaper alternative for capsaicin. Warming or heating ointment of nonivamide is used for temporary relief of pain from conditions such as rheumatism, arthritis, lumbao, muscular aches, sprains and strains, sporting injuries and other conditions where local warmth is beneficial. Finalgon is one of the common product utilizing nonivamide for this purpose. Nonivamide is also used as an incapacitant spray, affecting the assailed person’s eyes, causing intense pain and swelling.

Preparation

From nonanyl chloride and vanillylamine.

References

[1] https://www.scbt.com/scbt/product/nonivamide-2444-46-4 [2] https://pubchem.ncbi.nlm.nih.gov/compound/N-Vanillylnonanamide#section=Clinical-Trials [3] https://cot.food.gov.uk/sites/default/files/cot/cotsection.pdf

Uses

analgesic (topical), depletes Substance P

Chemical Properties

n-Nonanyl-4-hydroxy-3-methoxybenzyl-amide is an odorless compound, but has a pungent, burning taste

Definition

ChEBI: A capsaicinoid that is the carboxamide resulting from the formal condensation of the amino group of 4-hydroxy-3-methoxybenzylamine with the carboxy group of nonanoic acid. It is the active ingredient in many pepper sprays.

Chemical Properties

solid

Uses

N-Vanillylnonanamide is a synthetic analogue of Capsaicin (175680) with similar bioactivity.

InChI:InChI=1/C17H27NO3/c1-3-4-5-6-7-8-9-17(20)18-13-14-10-11-15(19)16(12-14)21-2/h10-12,19H,3-9,13H2,1-2H3,(H,18,20)

Synthetic route

Vanillylamin (1196-92-5) + nonanoic acid (112-05-0) → Nonivamide (2444-46-4)

Conditions	Yield
With 2-((N,N-diisopropylamino)methyl)-4-cyanophenylboronic acid In fluorobenzene at 85℃; for 3.5h; Reagent/catalyst; Solvent; Temperature; Molecular sieve; Green chemistry;	99%
With SiO2-H3BO3 In toluene for 7h; Reflux;	91%
With boric acid In toluene at 130℃; for 8h; Concentration; Temperature;	87.4%

Nonanoyl chloride (764-85-2) + Vanillylamin (1196-92-5) → Nonivamide (2444-46-4)

Conditions	Yield
Stage #1: Vanillylamin With sodium hydrogencarbonate In chloroform; water at 20℃; for 0.75h; Stage #2: Nonanoyl chloride In chloroform; water at 20 - 40℃; for 1h;	94%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃;	88.6%
In diethyl ether; N,N-dimethyl-formamide Ambient temperature;	59%
With diethyl ether
With triethylamine

Nonanoyl chloride (764-85-2) + vanillylamine hydrochloride (7149-10-2) → Nonivamide (2444-46-4)

Conditions	Yield
With sodium hydrogencarbonate In dichloromethane; water at 20 - 42℃; for 2.5h; Temperature;	91.5%
Stage #1: vanillylamine hydrochloride With sodium hydroxide In water; N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere; Cooling with ice; Stage #2: Nonanoyl chloride In tetrahydrofuran; water; N,N-dimethyl-formamide at 20℃; for 18h; Inert atmosphere; Cooling with ice;	60.51%

3-methoxy-4-(triisopropylsilyloxy)-N-(nonanoyl)benzylamine (871570-36-4) → Nonivamide (2444-46-4)

Conditions	Yield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 4h; Inert atmosphere;	84%
With tetrabutyl ammonium fluoride In tetrahydrofuran	81%

nonanoic acid (112-05-0) + vanillylamine hydrochloride (7149-10-2) → Nonivamide (2444-46-4)

Conditions	Yield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 0 - 20℃; Temperature;	81.1%

N-(4-benzyloxy-3-methoxy-benzyl)-nonanamide (102811-97-2) → Nonivamide (2444-46-4)

Conditions	Yield
With palladium on activated charcoal; ethanol Hydrogenation;

2-methoxy-phenol (90-05-1) + N-hydroxymethyl-nonamide → Nonivamide (2444-46-4)

Conditions	Yield
With hydrogenchloride

3-methoxy-4-(triisopropylsilyloxy)benzonitrile (222622-85-7) → Nonivamide (2444-46-4)

Conditions	Yield
Multi-step reaction with 3 steps 1: LiAlH4 / tetrahydrofuran / 20 °C 2: 4-DMAP; pyridine / CH2Cl2 / 0 - 20 °C 3: 81 percent / TBAF / tetrahydrofuran View Scheme

3-methoxy-4-(triisopropylsilyloxy)-benzylamine (222620-67-9) → Nonivamide (2444-46-4)

Conditions	Yield
Multi-step reaction with 2 steps 1: 4-DMAP; pyridine / CH2Cl2 / 0 - 20 °C 2: 81 percent / TBAF / tetrahydrofuran View Scheme

3-methoxy-4-hydroxybenzonitrile (4421-08-3) → Nonivamide (2444-46-4)

Conditions	Yield
Multi-step reaction with 4 steps 1: 91 percent / imidazole / dimethylformamide / 20 °C 2: LiAlH4 / tetrahydrofuran / 20 °C 3: 4-DMAP; pyridine / CH2Cl2 / 0 - 20 °C 4: 81 percent / TBAF / tetrahydrofuran View Scheme

nonanoic acid (112-05-0) → Nonivamide (2444-46-4)

Conditions	Yield
Multi-step reaction with 2 steps 1: oxalyl chloride / 3 h 2: 59 percent / dimethylformamide; diethyl ether / Ambient temperature View Scheme
Multi-step reaction with 2 steps 1.1: thionyl chloride / 4 h / Reflux 2.1: sodium hydrogencarbonate / water; chloroform / 0.75 h / 20 °C 2.2: 1 h / 20 - 40 °C View Scheme

Nonanoyl chloride (764-85-2) → Nonivamide (2444-46-4)

Conditions	Yield
Multi-step reaction with 2 steps 1: pyridine 2: palladium/charcoal; ethanol / Hydrogenation View Scheme

3-methoxy-4-(phenylmethoxy)benzaldehyde (2426-87-1) → Nonivamide (2444-46-4)

Conditions	Yield
Multi-step reaction with 3 steps 1: ethanolic NH3; Raney nickel / 50 - 60 °C / 44130.5 Torr / Hydrogenation 2: pyridine 3: palladium/charcoal; ethanol / Hydrogenation View Scheme

4-benzyloxy-3-methoxy-benzylamine (67023-43-2) → Nonivamide (2444-46-4)

Conditions	Yield
Multi-step reaction with 2 steps 1: pyridine 2: palladium/charcoal; ethanol / Hydrogenation View Scheme

3-methoxy-4-(4,5-dimethoxy-2-nitrobenzyloxy)-N-(nonanoyl)benzylamine → Nonivamide (2444-46-4)

Conditions	Yield
In tetrahydrofuran for 0.0833333h; laser photolysis;

(4,5-dimethoxy-2-nitrobenzyl)-2'-methoxy-4'-(nonanamidomethyl)phenylcarbonate (887256-95-3) → Nonivamide (2444-46-4)

Conditions	Yield
In tetrahydrofuran for 0.0833333h; laser photolysis;

Vanillylamin (1196-92-5) + nonanamide (1120-07-6) → Nonivamide (2444-46-4)

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In N,N-dimethyl-formamide at 20℃; for 15h;

4-hydroxymethyl-2-methoxyphenol (498-00-0) → Nonivamide (2444-46-4)

Conditions	Yield
Multi-step reaction with 3 steps 1.1: oxygen / toluene / 3 h / 70 °C / Sealed tube 2.1: D-glucose; L-alanin; ammonium chloride; glucose dehydrogenase; amine transaminase; L-alanine dehydrogenase; NADH; sodium hydroxide / dimethyl sulfoxide / 22 h / 37 °C / pH 8.2 / Darkness; Enzymatic reaction 3.1: sodium hydrogencarbonate / water; chloroform / 0.75 h / 20 °C 3.2: 1 h / 20 - 40 °C View Scheme
Multi-step reaction with 3 steps 1: oxygen / toluene / 3 h / 70 °C / Sealed tube 2: D-glucose; L-alanin; ammonium chloride; glucose dehydrogenase; amine transaminase; L-alanine dehydrogenase; NADH; sodium hydroxide / dimethyl sulfoxide / 22 h / 37 °C / pH 8.2 / Darkness; Enzymatic reaction 3: lipase / tert-Amyl alcohol / 48 h / 45 °C / Molecular sieve; Enzymatic reaction View Scheme
Multi-step reaction with 4 steps 1.1: oxygen / toluene / 3 h / 70 °C / Sealed tube 2.1: rac-Pro-OH / 24 h / 20 °C / Inert atmosphere 3.1: D-glucose; L-alanin; ammonium chloride; glucose dehydrogenase; amine transaminase; L-alanine dehydrogenase; NADH; sodium hydroxide / dimethyl sulfoxide / 90 h / 37 °C / pH 8.2 / Darkness; Enzymatic reaction 4.1: sodium hydrogencarbonate / water; chloroform / 0.75 h / 20 °C 4.2: 1 h / 20 - 40 °C View Scheme

4-(4-hydroxyphenyl-3-methoxy)-4-hydroxy-2-butanone (61152-59-8) → Nonivamide (2444-46-4)

Conditions	Yield
Multi-step reaction with 2 steps 1.1: D-glucose; L-alanin; ammonium chloride; glucose dehydrogenase; amine transaminase; L-alanine dehydrogenase; NADH; sodium hydroxide / dimethyl sulfoxide / 90 h / 37 °C / pH 8.2 / Darkness; Enzymatic reaction 2.1: sodium hydrogencarbonate / water; chloroform / 0.75 h / 20 °C 2.2: 1 h / 20 - 40 °C View Scheme
Multi-step reaction with 2 steps 1: D-glucose; L-alanin; ammonium chloride; glucose dehydrogenase; amine transaminase; L-alanine dehydrogenase; NADH; sodium hydroxide / dimethyl sulfoxide / 90 h / 37 °C / pH 8.2 / Darkness; Enzymatic reaction 2: lipase / tert-Amyl alcohol / 48 h / 45 °C / Molecular sieve; Enzymatic reaction View Scheme
Multi-step reaction with 2 steps 1: ammonium chloride; NADH; L-alanine dehydrogenase; glucose dehydrogenase; chromobacterium violaceum amine transaminase; L-alanin; D-Glucose / dimethyl sulfoxide / 92 h / 37 °C / pH 8.2 / Darkness; Enzymatic reaction 2: lipase / tert-Amyl alcohol / 48 h / 45 °C / Molecular sieve; Enzymatic reaction View Scheme
Multi-step reaction with 3 steps 1: ammonium chloride; NADH; L-alanine dehydrogenase; glucose dehydrogenase; L-alanin; D-Glucose / dimethyl sulfoxide / 70 h / 37 °C / pH 8.2 / Enzymatic reaction 2: ammonium chloride; NADH; L-alanine dehydrogenase; glucose dehydrogenase; chromobacterium violaceum amine transaminase; L-alanin; D-Glucose / dimethyl sulfoxide / 17 h / 37 °C / pH 8.2 / Darkness; Enzymatic reaction 3: lipase / tert-Amyl alcohol / 48 h / 45 °C / Molecular sieve; Enzymatic reaction View Scheme

vanillin (121-33-5) → Nonivamide (2444-46-4)

Conditions	Yield
Multi-step reaction with 2 steps 1.1: D-glucose; L-alanin; ammonium chloride; glucose dehydrogenase; amine transaminase; L-alanine dehydrogenase; NADH; sodium hydroxide / dimethyl sulfoxide / 22 h / 37 °C / pH 8.2 / Darkness; Enzymatic reaction 2.1: sodium hydrogencarbonate / water; chloroform / 0.75 h / 20 °C 2.2: 1 h / 20 - 40 °C View Scheme
Multi-step reaction with 2 steps 1: D-glucose; L-alanin; ammonium chloride; glucose dehydrogenase; amine transaminase; L-alanine dehydrogenase; NADH; sodium hydroxide / dimethyl sulfoxide / 22 h / 37 °C / pH 8.2 / Darkness; Enzymatic reaction 2: lipase / tert-Amyl alcohol / 48 h / 45 °C / Molecular sieve; Enzymatic reaction View Scheme
Multi-step reaction with 3 steps 1.1: rac-Pro-OH / 24 h / 20 °C / Inert atmosphere 2.1: D-glucose; L-alanin; ammonium chloride; glucose dehydrogenase; amine transaminase; L-alanine dehydrogenase; NADH; sodium hydroxide / dimethyl sulfoxide / 90 h / 37 °C / pH 8.2 / Darkness; Enzymatic reaction 3.1: sodium hydrogencarbonate / water; chloroform / 0.75 h / 20 °C 3.2: 1 h / 20 - 40 °C View Scheme

C11H14O4 → Nonivamide (2444-46-4)

Conditions	Yield
Multi-step reaction with 3 steps 1: ammonium chloride; NADH; L-alanine dehydrogenase; glucose dehydrogenase; L-alanin; D-Glucose / dimethyl sulfoxide / 116 h / 20 °C / pH 8.2 / Enzymatic reaction 2: ammonium chloride; NADH; L-alanine dehydrogenase; glucose dehydrogenase; chromobacterium violaceum amine transaminase; L-alanin; D-Glucose / dimethyl sulfoxide / 17 h / 37 °C / pH 8.2 / Darkness; Enzymatic reaction 3: lipase / tert-Amyl alcohol / 48 h / 45 °C / Molecular sieve; Enzymatic reaction View Scheme
Multi-step reaction with 4 steps 1: ammonium chloride; NADH; L-alanine dehydrogenase; glucose dehydrogenase; L-alanin; D-Glucose / dimethyl sulfoxide / 116 h / 20 °C / pH 8.2 / Enzymatic reaction 2: rac-Pro-OH / 24 h / 20 °C / Inert atmosphere 3: ammonium chloride; NADH; L-alanine dehydrogenase; glucose dehydrogenase; chromobacterium violaceum amine transaminase; L-alanin; D-Glucose / dimethyl sulfoxide / 92 h / 37 °C / pH 8.2 / Darkness; Enzymatic reaction 4: lipase / tert-Amyl alcohol / 48 h / 45 °C / Molecular sieve; Enzymatic reaction View Scheme

Nonivamide (2444-46-4) + nitroveratryloxycarbonyl chloride (42855-00-5) → (4,5-dimethoxy-2-nitrobenzyl)-2'-methoxy-4'-(nonanamidomethyl)phenylcarbonate (887256-95-3)

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere;	100%

Nonivamide (2444-46-4) + tert-butyldimethylsilyl chloride (18162-48-6) → C23H41NO3Si

Conditions	Yield
With triethylamine In dichloromethane for 14h; Inert atmosphere;	99%

Nonivamide (2444-46-4) → N-(3,4-dihydroxybenzyl)nonanamide (139446-83-6)

Conditions	Yield
With aluminium(III) iodide; calcium oxide In acetonitrile at 80℃; for 18h;	97%
With aluminium(III) iodide; diisopropyl-carbodiimide In acetonitrile at 80℃; for 18h;	93%
With aluminium(III) iodide; diisopropyl-carbodiimide In acetonitrile at 80℃; for 18h;	93%

phosphoric acid dibenzyl ester (1623-08-1) + Nonivamide (2444-46-4) → C31H40NO6P

Conditions	Yield
With dmap; N-ethyl-N,N-diisopropylamine In tetrachloromethane; acetonitrile at 0℃; for 1h;	92%

Nonivamide (2444-46-4) + 2-bromoethanol (540-51-2) → N-(4-O-glycol-3-methoxybenzyl)-nonamide (143827-59-2)

Conditions	Yield
Stage #1: Nonivamide With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 2h; Stage #2: 2-bromoethanol In N,N-dimethyl-formamide at 120℃;	87%

Nonivamide (2444-46-4) + ethyl bromoacetate (105-36-2) → 2-(2-methoxy-4-(nonanamidomethyl)phenoxy)acetic acid

Conditions	Yield
Stage #1: Nonivamide; ethyl bromoacetate With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 12h; Stage #2: With sodium hydroxide In ethanol at 20℃; for 5h; Stage #3: In ethanol; water pH=2;	85.4%

Nonivamide (2444-46-4) + epichlorohydrin (106-89-8) → N-<4-(2,3-epoxypropoxy)-3-methoxybenzyl>nonanamide (153601-17-3)

Conditions	Yield
With sodium hydroxide In ethanol; water at 80℃; for 3h;	85%

Nonivamide (2444-46-4) + 2-chloromethylpyridine hydrochloride (6959-47-3) → N-<4-(pyridylmethoxy)-3-methoxybenzyl>nonanamide

Conditions	Yield
With sodium hydroxide for 7h; Heating;	82%

2-(chloroethyl)piperidine hydrochloride (111781-62-5) + Nonivamide (2444-46-4) → N-<4-(piperidylethoxy)-3-methoxybenzyl>nonanamide

Conditions	Yield
With sodium hydroxide for 7h; Heating;	78%

Nonivamide (2444-46-4) + 2-Bromo-4'-methoxyacetophenone (2632-13-5) → 3-methoxy-4-(4'-methoxyacetophenone-2-oxy)-N-nonanoylbenzylamine

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃;	74%
Stage #1: Nonivamide With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; Inert atmosphere; Stage #2: 2-Bromo-4'-methoxyacetophenone In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; Inert atmosphere;	71%

Nonivamide (2444-46-4) + 2-(dimethylamino)ethyl chloride (107-99-3) → Nonanoic acid 4-(2-dimethylamino-ethoxy)-3-methoxy-benzylamide

Conditions	Yield
With sodium hydroxide for 7h; Heating;	73%

Nonivamide (2444-46-4) + 2-benzyloxybenzoyl chloride (4349-62-6) → C31H37NO5

Conditions	Yield
With triethylamine In dichloromethane at 20℃;	68.5%

Nonivamide (2444-46-4) + 2-(diethylamino)ethyl chloride (100-35-6) → Nonanoic acid 4-(2-diethylamino-ethoxy)-3-methoxy-benzylamide

Conditions	Yield
With sodium hydroxide for 7h; Heating;	68%

Nonivamide (2444-46-4) + 6-nitroveratrylbromide (53413-67-5) → 3-methoxy-4-(4,5-dimethoxy-2-nitrobenzyloxy)-N-(nonanoyl)benzylamine

Conditions	Yield
With potassium tert-butylate In tetrahydrofuran at 20℃;	66%
Stage #1: Nonivamide With potassium tert-butylate In tetrahydrofuran at 20℃; for 0.416667h; Inert atmosphere; Stage #2: 6-nitroveratrylbromide In tetrahydrofuran at 20℃; for 16h; Inert atmosphere;	66%

Nonivamide (2444-46-4) + 3-monochloro-1,2-propanediol (96-24-2) → Glyceryl novinamide (143827-57-0)

Conditions	Yield
With sodium hydroxide for 1h; Heating;	64%

Nonivamide (2444-46-4) + 2-chloro-ethanol (107-07-3) → N-(4-O-glycol-3-methoxybenzyl)-nonamide (143827-59-2)

Conditions	Yield
With sodium hydroxide at 100℃; for 1h;	61%

succinic acid anhydride (108-30-5) + Nonivamide (2444-46-4) → N-(4-O-succinic acid-3-methoxybenzyl)-nonamide (136449-08-6)

Conditions	Yield
In N,N-dimethyl-formamide at 100℃; for 1h;	48%
In neat (no solvent) at 110℃; for 0.25h;

Nonivamide (2444-46-4) + sodium monochloroacetic acid (3926-62-3) → N-(4-O-acetic acid sodium-3-methoxybenzyl)-nonamide (146690-24-6)

Conditions	Yield
With sodium hydroxide for 2h; Heating;	44%

Nonivamide (2444-46-4) + methyl iodide (74-88-4) → N-(3,4-dimethoxybenzyl)-8-methylnonanamide

Conditions	Yield
With potassium carbonate In acetone for 18h; Heating;	37%

Nonivamide (2444-46-4) → nonanoic acid [6,2'-dihydroxy-5,3'-dimethoxy-5'-(nonanoylamino-methyl)-biphenyl-3-ylmethyl]-amide

Conditions	Yield
With sodium carbonate; potassium hexacyanoferrate(III) In water; N,N-dimethyl-formamide at 20℃;	37%

Nonivamide (2444-46-4) + C13H14BrNO5S (1417436-63-5) → C29H37BrN2O5 (1417436-74-8)

Conditions	Yield
With potassium hydroxide In tetrahydrofuran	32%
With caesium carbonate In acetone

Nonivamide (2444-46-4) + (8-cyano-7-(methoxymethoxy)quinolin-2-yl)methyl methanesulfonate (1417436-71-5) → C30H37N3O5 (1417436-80-6)

Conditions	Yield
With potassium hydroxide In tetrahydrofuran	32%
With caesium carbonate In acetone

2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1->4)-2,3,6-tri-O-acetyl-β-D-glucopyranosyl bromide (70223-97-1) + Nonivamide (2444-46-4) → C43H61NO20

Conditions	Yield
With tetrabutylammomium bromide; potassium carbonate; potassium hydroxide In dichloromethane; water at 20℃;	25.7%

Nonivamide (2444-46-4) + phenyl BODIPY → C36H45BFN3O3

Conditions	Yield
Stage #1: phenyl BODIPY With trimethylsilyl trifluoromethanesulfonate In dichloromethane at 4 - 5℃; for 0.05h; Stage #2: Nonivamide In dichloromethane at 20℃; for 0.166667h;	17%

Upstream product

• 2444-37-3 (METHYLTHIO)ACETIC ACID 
• 2444-36-2 2-Chlorophenylacetic acid 
• 24443-38-7 2-{2-nitro-4,5-dimethoxyphenyl}-3-phenylacrylonitrile 
• 24443-15-0 1,3-DIBROMO-3-METHYLBUTANE 
• 24443-11-6 (2E)-3-chloro-2-methylprop-2-enal 
• 2444-29-3 1-methyl-2-(4-nitrophenoxy)benzene 
• 2444-28-2 2,6-di-tert-butylhydroquinone 
• 244-42-8 5H-Indeno[1,2-c]pyridine 
• 24442-76-0 2,4,6,8-Decatetryne 
• 2444-27-1 3-tert-butyl-4-hydroxyphenyl benzoate 
• 24442-69-1 1,4-PENTADIYNE 
• 24442-68-0 3,3,5-trimethylcyclohexyl formate 
• 24442-57-7 1,2-Dibromoethyl acetate 
• 2444-24-8 4-(Benzyloxy)-2,6-di-tert-butylphenol 

Downstream Products

• 465-42-9 Capsanthin 

Recommend Products

• 1196-92-5  Vanillylamin 
• 1731-84-6  nonanoic acid methyl ester 
• 67-56-1  methanol 
• 2444-46-4  Nonivamide 
• 112-05-0  nonanoic acid 
• 7149-10-2  vanillylamine hydrochloride 
• 764-85-2  Nonanoyl chloride 
• 67023-43-2  4-benzyloxy-3-methoxy-benzylamine 
• 2426-87-1  3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 149555-76-0  N-<4-<(dimethylcarbamoyl)thio>-3-methoxybenzyl>nonanamide