2836-32-0

Usage

Uses

Used in Electroless Plating and Textile Finishing:
Sodium glycolate is used as a buffer in electrodeless plating and textile finishing, where it helps in stabilizing the pH and improving the overall process efficiency.
Used in Pharmaceutical Industry:
Sodium glycolate is used as a disintegrant, suspending agent, gelling agent, and buffering agent in the pharmaceutical grade for tablets and capsules. Its properties contribute to the improved formulation and performance of these medicinal products.
Used in Cosmetics and Personal Care Products:
In the cosmetics and personal care industry, sodium glycolate is utilized as an exfoliant, pH adjuster, skin-conditioning agent, and a flavoring agent. Its versatility in this sector allows for a wide range of applications, enhancing the quality and effectiveness of various products.

Purification Methods

Precipitate it from aqueous solution by adding EtOH and dry it in air. Also recrystallise it from H2O, where its solubility is 38% at 0o and 61% at100o. [Beilstein 3 III 370, 3 IV 573.]

InChI:InChI=1/C2H4O3.Na/c3-1-2(4)5;/h3H,1H2,(H,4,5);/q;+1/p-1

Upstream product

• 107-21-1 ethylene glycol 
• 105-36-2 ethyl bromoacetate 
• 3926-62-3 sodium monochloroacetic acid 
• 131543-46-9 Glyoxal 
• 492-62-6 alpha-D-glucopyranose 
• 40010-55-7 ¹³C-C₁-glucopyranose 
• 56-81-5 glycerol 
• 7664-41-7 ammonia 
• 7440-23-5 sodium 
• 9004-34-6 cellulose 
• 50-99-7 D-glucose 
• 79-11-8 chloroacetic acid 
• 1310-73-2 sodium hydroxide 
• 79-14-1 glycolic Acid 

Downstream Products

• 34128-01-3 trisodium 2-[(carboxymethyl)oxy]succinate 
• 38945-27-6 carboxymethyl oxysuccinic acid 
• 298-12-4 Glyoxilic acid 
• 64-18-6 formic acid 
• 110-15-6 succinic acid 
• 64-19-7 acetic acid 
• 102991-08-2 4-Methoxybenzyl 2-hydroxyacetate 
• 95734-82-0 nedaplatin 
• 7782-53-8 copper(II) glycolate 
• 62-76-0 sodium oxalate 
• 4856-97-7 2-(Hydroxymethyl)benzimidazole 
• 167403-92-1 4-tert-butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenyl)thio-4-pyrimidinyl)benzenesulfonamide 
• 146531-72-8 N-[6-(2-hydroxy-ethoxy)-5-(p-methoxyphenyl)-4-pyrimidinyl]-p-toluenesulfon-amide 
• 150727-21-2 4-tert-butyl-N-[6-(2-hydroxy-ethoxy)-5-(3-methoxy-phenoxy)-4-pyrimidinyl]-benzenesulphonamide 

Relevant academic research and scientific papers

Homogeneous Reforming of Aqueous Ethylene Glycol to Glycolic Acid and Pure Hydrogen Catalyzed by Pincer-Ruthenium Complexes Capable of Metal–Ligand Cooperation

Glycolic acid is a useful and important α-hydroxy acid that has broad applications. Herein, the homogeneous ruthenium catalyzed reforming of aqueous ethylene glycol to generate glycolic acid as well as pure hydrogen gas, without concomitant CO2 emission, is reported. This approach provides a clean and sustainable direction to glycolic acid and hydrogen, based on inexpensive, readily available, and renewable ethylene glycol using 0.5 mol % of catalyst. In-depth mechanistic experimental and computational studies highlight key aspects of the PNNH-ligand framework involved in this transformation.

HYDROGEN PRODUCTION FROM ETHYLENE GLYCOL UNDER BASIC CONDITIONS

Disclosed is a method of producing hydrogen from monoethylene glycol. The method includes mixing an aqueous base, monoethylene glycol, and an iridium chloride (IrCl3) catalyst solubilized therein under conditions sufficient to produce hydrogen from the ethylene glycol present in the basic homogeneous aqueous solution.

Preparation method for 2,4-dichlorophenoxyacetic acid

The invention provides a preparation method for 2,4-dichlorophenoxyacetic acid. The preparation method comprises the following steps: A) reacting a divalent salt of glycolic acid as shown in a formula(I) with 1,2,4-trichlorobenzene under the action of a catalyst so as to produce 2,4-dichlorophenoxyacetate as shown in a formula (II); and B) acidizing 2,4-dichlorophenoxyacetate so as to obtain 2,4-dichlorophenoxyacetic acid. According to the invention, 1,2,4-trichlorobenzene is creatively used for replacing phenol and chlorophenol and subjected to a condensation reaction with glycolate so as toproduce 2,4-dichlorophenoxyacetate, and hydrolysis is carried out so as to prepare 2,4-dichlorophenoxyacetic acid; so such a technical scheme effectively avoids the usage of phenol or chlorophenol, overcomes the problems of peculiar smell of an operation place and production of waste gas, waste water and industrial residues, greatly improves the operation environment of the operation place and produces good environmental protection benefits, and the reaction has high yield and purity.

Efficient and Bio-inspired Conversion of Cellulose to Formic Acid Catalyzed by Metalloporphyrins in Alkaline Solution

A bio-inspired approach for efficient conversion of cellulose to formic acid (FA) was developed in an aqueous alkaline medium. Metalloporphyrins mimicking cytochrome P450 exhibit efficiently and selectively catalytic performance in catalytic conversion of cellulose. High yield of FA about 63.7% was obtained by using sulfonated iron(III) porphyrin as the catalyst and O2 as the oxidant. Iron(III)-peroxo species, TSPPFeIIIOO?, was involved to cleave the C-C bonds of gluconic acid to FA in this catalytic system. This approach used relatively high concentration of cellulose and ppm concentration of catalyst. This work may provide a bio-inspired route to efficient conversion of cellulose to FA.

Hydrolysis kinetics of chloroacetic acid with sodium hydroxide under strong alkaline conditions

The hydrolysis of chloroacetic acid and sodium hydroxide is carried out at 45-85 °C by using equal mole of sodium chloroacetate and alkali. Using reasonable approximation, the hydrolysis reaction is proved to be a second-order reaction when the conversion is less than 95 % and the kinetic rate coefficients are determined. The activate energy is calculated 103 kJ mol-1.

Chemometric approaches on glycerol oxidation with H2O 2 over supported gold nanoparticles

This paper reports a chemometric study of effects of the catalyst preparation method and reaction conditions on the efficiency of glycerol oxidation catalyzed by gold nanoparticles supported on activated carbon using H2O2 as oxidant. Factorial designs and principal component analysis were used for the evaluation of experimental conditions and reaction performance. Evaluating catalyst preparation conditions we found that larger Au nanoparticles are obtained using HAuCl4 in higher concentration. Glycerol conversion and production of glycerate and tartronate were higher using catalysts prepared with low polyvinyl alcohol (PVA) to Au ratio and low Au content. Higher HAuCl4 concentrations resulted in larger Au nanoparticles, which contributed to higher glycolate production. Evaluating reaction conditions we found that the influence of H2O2 to glycerol ratio was insignificant. Glycerol conversion and production of glycerate and tartronate were higher at lower temperature. Increasing H 2O2 to glycerol ratio contributed to higher glycolate production. Glycerol to Au ratio has a smaller influence on the reaction course.

Bismuth as a modifier of Au-Pd catalyst: Enhancing selectivity in alcohol oxidation by suppressing parallel reaction

Bi has been widely employed as a modifier for Pd and Pt based catalyst mainly in order to improve selectivity. We found that when Bi was added to the bimetallic system AuPd, the effect on activity in alcohol oxidation mainly depends on the amount of Bi regardless its position, being negligible when Bi was 0.1 wt% and detectably negative when the amount was increased to 3 wt%. However, the selectivity of the reactions notably varied only when Bi was deposited on the surface of metal nanoparticles suppressing parallel reaction in both benzyl alcohol and glycerol oxidation. After a careful characterization of all the catalysts and additional catalytic tests, we concluded that the Bi influence on the activity of the catalysts could be ascribed to electronic effect whereas the one on selectivity mainly to a geometric modification. Moreover, the Bi-modified AuPd/AC catalyst showed possible application in the production of tartronic acid, a useful intermediate, from glycerol.

MACROMOLECULES MODIFIED WITH ELECTROPHILIC GROUPS AND METHODS OF MAKING AND USING THEREOF

Described herein are macromolecules modified with electrophilic groups and methods of making and using thereof. The preparation of a thiol-reactive, electrophililic derivative of HA in order to prepare “crosslinker-free” hydrogels are described as well as compounds and methods that are capable of coupling two or more molecules, such as macromolecules, under mild conditions. Specifically disclosed is the introduction of reactive bromo- and iodoacetate functionalities at the hydroxyl groups that are abundantly present on the HA polymer. The “crosslinker-free” hydrogels described have numerous applications including, but not limited to, drug delivery, small molecule delivery, wound healing, burn injury healing, tissue regeneration/engineering, cell culturing, and bio-artificial materials.

Microgel-stabilized gold nanoclusters: Powerful "quasi-homogeneous" catalysts for the aerobic oxidation of alcohols in water

Gold nanoclusters of small size (2.5 nm) and narrow size distribution were synthesized in solution using tailor-made soluble cross-linked polymers (microgels) as exotemplates and stabilizers. The resulting microgel-stabilized nanoclusters could be conveniently isolated by precipitation, stored in the solid state, and redispersed in water and polar organic solvents. They were found to exhibit remarkable catalytic activity (average TOF up to 960 h-1) in the aerobic oxidation of benzylic and aliphatic alcohols and also of polyols in water under mild conditions (50-70 °C, 1-3 atm O2).

METHOD FOR PRODUCING CARBOXYLIC ACID AND/OR ITS SALT

PROBLEM TO BE SOLVED: To provide an industrially practicable method for producing a carboxylic acid and/or its salt by oxidizing the corresponding alcohol with molecular oxygen using a highly durable catalyst. SOLUTION: The method for producing the carboxylic acid and/or its salt comprises oxidizing the corresponding alcohol with molecular oxygen. Specifically, this method comprises carrying out the oxidation in an aqueous medium in the presence of a catalyst with gold-containing particles carried on a carrier containing titanium and/or zirconium. This method is excellent in high performance and catalyst durability.