HSP90 C-terminal inhibitors

July 31, 2024

• Title:       

  HSP90 C-terminal inhibitors

• Image Source:

  Development of Phenyl Cyclohexylcarboxamides as a Novel Class of Hsp90 C-terminal Inhibitors

• Mark:

  Figure 1

• Associated context:

  Subsequent studies revealed that the benzamide side chain of novobiocin is important for anti-proliferative activity and modification of this side chain produced several promising compounds, such as KU174 (Figure 1).