81-88-9Relevant articles and documents
Rhodamine-based 'turn-on' fluorescent probe for Cu(II) and its fluorescence imaging in living cells
Tian, Mao-Zhong,Hu, Ming-Ming,Fan, Jiang-Li,Peng, Xiao-Jun,Wang, Jing-Yun,Sun, Shi-Guo,Zhang, Rong
, p. 2916 - 2919 (2013)
A novel rhodamine spirolactam derivative 3′,6′- Bis(diethylamino)-2-(2-hydroxyethylamino) spiro[isoindoline-1,9′-xanthen]- 3-one (RO1) was synthesized, and characterized by high-resolution mass spectrometry (HRMS), X-ray crystallography, Infrared spectroscopy (IR), and 1H NMR and 13C NMR spectroscopy. RO1 exhibited highly sensitive and exclusively selective fluorescence response toward Cu2+ over other metal ions with a detection limit of 0.56 ppb in mixed aqueous solution. The fluorescence was pH-independent in the wide range pH 3.1-11.6. The turn-on fluorescence enhancement of the probe is based on Cu2+ induced ring-opening mechanism of the rhodamine spirolactam. Moreover, by means of fluorescence microscopy experiments, it was demonstrated that RO1 could monitor trace Cu2+ changes by live cell imaging.
Perimedine-linked rhodamine dye in visual sensing of Al3+, Fe3+ and Fe2+ ions in aqueous organic medium under different experimental conditions
Mondal, Subhendu,Ghosh, Kumaresh
, p. 645 - 652 (2019)
Perimedine labelled rhodamine dye 1 has been designed and synthesised. Metal ion binding studies of 1 have been performed in CH3CN/H2O (3:1, v/v, 10 mM Tris-HCl buffer, pH = 6.90). Compound 1 senses multiple metal ions such as Al3+, Fe3+ and Fe2+ by exhibiting turn on fluorescence and colour change (colourless to pink) under different experimental conditions. Concentration variation distinguishes Al3+ from Fe3+ ion. At low concentration (c = 1 x 10?4 M), only Al3+ ion can exhibit turn on fluorescence with sharp colour change. Sensing of Fe2+ ion through turn on fluorescence and colour change has been possible via in situ oxidation by following Fenton’s reaction.
Development of a rhodamine-benzimidazol hybrid derivative as a novel FRET based chemosensor selective for trace level water
Pal, Siddhartha,Mukherjee, Manjira,Sen, Buddhadeb,Lohar, Somenath,Chattopadhyay, Pabitra
, p. 21608 - 21611 (2014)
A newly designed rhodamine-benzimidazol hybrid molecule has been developed as a FRET-based chemosensor for the selective detection of trace level water in both polar protic and aprotic organic solvents. This journal is the Partner Organisations 2014.
Rapid and selective visualization of mitochondrial hypochlorite by a red region water-soluble fluorescence probe
Cao, Xiao-Qun,Huang, Xiao-Qing,Shen, Shi-Li,Wang, Tian-Ran,Zhang, Xiao-Fan
, (2021)
Hypochlorite (?OCl) has long been recognized as an effective microbicidal agent in immune system. Herein, we report the design, preparation and spectral characteristics of a ?OCl fluorescent probe (FI-Mito). The probe exhibited remarkable fluorescence turn-on signal in the red region upon ?OCl titration with the detection limit as low as 0.9 nM. FI-Mito displayed specific response for ?OCl in completely aqueous solution. Meanwhile, the introduction of quaternized pyridine realized mitochondria-targeting ability. FI-Mito was further applied to monitor the generation of endogenous ?OCl in the mitochondria of macrophage cells and mice. Therefore, it was established that FI-Mito may serve as a useful molecular tool for ?OCl detection in vivo.
Purification of rhodamine B by alcohol-modified air bubble flotation
Kodama, Koki,Oiwa, Mako,Saitoh, Tohru
, p. 1210 - 1214 (2021/05/17)
A simple and rapid method for the purification of a basic dye, Rhodamine B (RB) was developed. It was conducted by adding crude RB to an aqueous solution containing 0.2% (v/v) ethanol followed by air bubble flotation in a cylindrical glass vessel having a sintered glass filter at the bottom. By feeding air bubbles, RB was enriched into foam on the water surfaces within 3min, while source materials (phthalic acid and N,Ndiethyl-3-aminophenol), intermediate compound {2-(4-diethyl-amino-2-hydroxybenzoyl)}, and other organic impurities remained in the bulk aqueous solution. The foam containing enriched RB was taken up with suction and placed into another flotation vessel for repeated separation. An HPLC-grade RB was successfully obtained by 3-fold air bubble flotation.
A turn-on fluorescent and colorimetric chemodosimeter for selective detection of Au3+ ions in solution and in live cells: Via Au3+-induced hydrolysis of a rhodamine-derived Schiff base
Datta, Pallab,Ghosh, Aritri,Mandal, Debasish,Manna, Saikat Kumar,Mondal, Sanchita,Mukhopadhyay, Subrata,Pathak, Sudipta
, p. 7954 - 7961 (2020/06/17)
A chromogenic and off-on fluorogenic chemodosimeter (L) based on a naphthalene-rhodamine B derivative was designed, synthesized and characterized for the selective and sensitive detection of Au3+ ions in mixed acetonitrile aqueous medium in the presence of other competitive analytes. Probe L displayed a 696-fold turn-on fluorescence signal enhancement toward Au3+ ions with the detection limit of Au3+ of about 1.51 μM. In the presence of Au3+ ions, probe L also exhibited a visible color change from colorless to pink that could be easily identified by the naked eye. This colorimetric and fluorometric changes were mainly due to the Au3+ ion-triggered imine bond (CN) hydrolysis sensing mechanism. Moreover, theoretical calculations were performed to explain the experimental results. In addition to these features, the off-on probe was successfully used to monitor intracellular Au3+ ions in living MC3T3 cells through fluorescence imaging.
Based on rhodamine B derivatives of the fluorescent probe and its preparation method and application
-
Paragraph 0032-0034, (2017/08/25)
The invention provides a fluorescence probe based on a rhodamine B derivative as well as a preparation method and application thereof. The chemical structure formula of the rhodamine B derivative is shown as the specification. The rhodamine B derivative can be selectively combined with bivalent copper ions, and is changed into red color from no color; the fluorescence probe has a fluorescence enhanced effect and can realize naked-eye distinguishing detection, particularly the application of the fluorescence probe to the convenient detection of the copper ions in cells.
Rhodamine derived colorimetric and fluorescence mercury(ii) chemodosimeter for human breast cancer cell (MCF7) imaging
Kumari, Babli,Lohar, Sisir,Adhikari, Sangita,Sengupta, Archya,Chattopadhyay, Ansuman,Brand?o, Paula,Félix, Vítor,Das, Debasis
, p. 21797 - 21802 (2015/03/30)
Condensation of rhodaminehydrazone with naphthalene-1-carboxaldehyde generates a colourless probe, RDHDNAP that can selectively detect Hg2+ through generation of a pink color along with significant fluorescence enhancement. The binding constant and lowest detection limit for Hg2+ are 2.0 × 105 M-1 and 3 × 10-7 M respectively. Hg2+ imaging in human breast cancer cells (MCF7) under a fluorescence microscope is achieved. This journal is
XANTHENE-BASED PURPLE DYE COMPOUND, COLORING RESIN COMPOSITION FOR COLOR FILTER CONTAINING SAME AND COLOR FILTER USING SAME
-
Paragraph 0064, (2015/11/30)
The present disclosure relates to a purple dye compound for a color filter and a coloring resin composition for a color filter containing the same. The novel xanthene-based purple dye compound or the polymer dye compound obtained using the same as a monomer has superior solvent resistance and superior miscibility with a pigment in an organic solvent. Further, it exhibits superior heat resistance, chemical resistance, light resistance and brightness due to the homopolymer structure. Accordingly, a coloring resin composition containing the same can be used widely as a dye for synthetic resins and synthetic fibers, as a coloring agent for polymer materials, for a color filter used in LCDs, PDPs, etc., and so forth.
A rhodamine-quinoline based chemodosimeter capable of recognising endogenous OCl- in human blood cells
Goswami, Shyamaprosad,Das, Sangita,Aich, Krishnendu,Nandi, Prasanta Kumar,Ghoshal, Kakali,Quah, Ching Kheng,Bhattacharyya, Maitree,Fun, Hoong-Kun,Abdel-Aziz, Hatem A.
, p. 24881 - 24886 (2014/07/07)
A rhodamine-quinoline based chemodosimeter (RHQ) has been designed, synthesized and characterized in this paper. The structure of the sensor is confirmed through single crystal X-ray study. It detects hypochlorite (OCl -) selectively among other analytes studied. It showed colorimetric and orange-red fluorescence "turn-on" upon addition of OCl -. The OCl--promoted ring opening of the rhodamine spirolactam ring in RHQ evokes a large absorbance as well as fluorescence enhancement in water-acetonitrile (1/1, v/v) medium with no significant response to other competitive analytes. Furthermore, we demonstrate here that RHQ can endogenously detect OCl- in human blood cells (peripheral blood mononuclear cells). It also exhibits excellent performance in the "dip stick" method. The optimized structure of the probe is calculated by density functional theory calculations. Moreover, the limit of detection of the probe is in the 10-8 M range.
