Welcome to LookChem.com Sign In|Join Free

Cas Database

148-18-5

148-18-5

Identification

Synonyms:Sodium N,N-diethyldithiocarbamate;Carbamic acid, diethyldithio-, sodium salt;DEDC;Soxinol ESL;Diethyldithiocarbamic acid, sodium;Usaf ek-2596;DEDK;Ditiocarb sodium;Diethyldithiocarbamic acid, sodium salt;Thiocarb;GS 694A;NCI-C02835;DTC;DDC;

Post Buying Request Now

Safety information and MSDS view more

  • Signal Word:Warning

  • Hazard Statement:H315 Causes skin irritationH319 Causes serious eye irritation H400 Very toxic to aquatic life

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price view more

  • Manufacture/Brand
  • Product Description
  • Packaging
  • Price
  • Delivery
  • Purchase
  • Manufacture/Brand:Usbiological
  • Product Description:Sodium N-
  • Packaging:5mg
  • Price:$ 425
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Usbiological
  • Product Description:Sodium N-
  • Packaging:1g
  • Price:$ 333
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Medical Isotopes, Inc.
  • Product Description:DitiocarbSodium
  • Packaging:5 mg
  • Price:$ 950
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Matrix Scientific
  • Product Description:Sodium N,N-diethyldithiocarbamate(25% solution in water) >95%
  • Packaging:10g
  • Price:$ 59
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Matrix Scientific
  • Product Description:Sodium N,N-diethyldithiocarbamate(25% solution in water) >95%
  • Packaging:50g
  • Price:$ 103
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Crysdot
  • Product Description:Sodiumdiethylcarbamodithioate 98%
  • Packaging:100g
  • Price:$ 444
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Crysdot
  • Product Description:Sodiumdiethylcarbamodithioate 98%
  • Packaging:25g
  • Price:$ 144
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Crysdot
  • Product Description:Sodiumdiethylcarbamodithioate 98%
  • Packaging:5g
  • Price:$ 39
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:ChemScene
  • Product Description:Ditiocarbsodium 98.13%
  • Packaging:500mg
  • Price:$ 50
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:ChemScene
  • Product Description:Ditiocarbsodium 98.13%
  • Packaging:1g
  • Price:$ 60
  • Delivery:In stock
  • Buy Now

Relevant articles and documentsAll total 23 Articles be found

Novel imidazole derivatives as antifungal agents: Synthesis, biological evaluation, ADME prediction and molecular docking studies

Alt?nda?, Firuze Diyar,Sa?l?k, Begüm Nurpelin,Acar ?evik, Ulviye,I??kda?, ?lhan,?zkay, Yusuf,Karaca Gen?er, Hülya

, p. 887 - 894 (2019)

A series of 2-(substituteddithiocarbamoyl)-N-[4-((1H-imidazol-1-yl)methyl)phenyl]acetamide derivatives was designed and synthesized to combat the increasing incidence of drug-resistant fungal infections. All synthesized compounds were characterized by IR, 1H-NMR, 13C-NMR, and HRMS spectra and elemental analyses. Antifungal activity tests were performed against four different fungal strains. Molecular docking studies were performed to investigate the mode of action towards the fungal lanosterol 14α-demethylase, a cytochrome P450-dependent enzyme. ADME studies were carried out and a connection between activities and physicochemical properties of the target compounds was determined. Most of the final compounds exhibited significant activity against Candida albicans and Candida krusei with MIC50 value 12.5 μg/mL. The results of in vitro anti-Candida activity, a docking study and ADME prediction revealed that the newly synthesized compounds have potential anti-Candida activity and evidenced the most active derivative, 5b (2-Pyrrolidinthiocarbonylthio-N-[4-((1H-imidazol-1-yl)methyl)phenyl]acetamide), which can be further optimized as a lead compound.

Molecular structure, natural bond analysis, vibrational and electronic spectra, surface enhanced Raman scattering and Mulliken atomic charges of the normal modes of [Mn(DDTC)2] complex

Téllez S., Claudio A.,Costa, Anilton C.,Mondragón,Ferreira, Glaucio B.,Versiane,Rangel,Lima, G. Müller,Martin

, p. 95 - 107 (2016)

Theoretical and experimental bands have been assigned for the Fourier Transform Infrared and Raman spectra of the bis(diethyldithiocarbamate)Mn(II) complex, [Mn(DDTC)2]. The calculations have been based on the DFT/B3LYP method, second derivative spectra and band deconvolution analysis. The UV–vis experimental spectra were measured in acetonitrile solution, and the calculated electronic spectrum was obtained using the TD/B3LYP method with 6-311G(d, p) basis set for all atoms. Charge transfer bands and those d-d spin forbidden were assigned in the UV–vis spectrum. The natural bond orbital analysis was carried out using the DFT/B3LYP method and the Mn(II) hybridization leading to the planar geometry of the framework was discussed. Surface enhanced Raman scattering (SERS) was also performed. Mulliken charges of the normal modes were obtained and related to the SERS enhanced bands.

Solid-phase synthesis, crystal structure, and quantum chemical calculation of a molybdenum(II) complex with bis(diethyldithiocarbamate)

He, Guang-Yu,Bei, Feng-Li,Chen, Hai-Qun,Sun, Xiao-Qiang

, p. 481 - 486 (2006)

The complex Mo(Et2dtc)2 [Et2dtc: bis(diethyldithiocarbamate)] was synthesized by solid-phase reaction at room temperature and characterized by elemental analysis, powder XRD, IR, 1H NMR and TG/DTA. Its crystal structure was determined by X-ray single crystal diffraction. The crystals are monoclinic with space group P2 1/c, a=0.61800(12)nm; b=1.1540(2)nm; c=1.1610(2)nm; β=95.78(3)°; V=0.8238(3)nm3; D c=1.582g/cm 3; Z=2 F(000)=400; μ=1.285mm-1; R=0.0703; wR=0.2330; GOF=1.060. The coordination geometry of Mo atom, by four S anions from Et 2dtc ligand, is that of a slightly distorted planar square. Furthermore, the optimized geometry, charge distribution, and thermodynamic functions were calculated by quantum chemical method.

A 2H-MoS2/carbon cloth composite for high-performance all-solid-state supercapacitors derived from a molybdenum dithiocarbamate complex

Yan, Zhishuo,Zhao, Jixing,Gao, Qingsheng,Lei, Hao

, p. 11954 - 11964 (2021)

A molecular complex Mo2O2(μ-S)2(Et2dtc)2(dtc = dithiocarbamate) is prepared and loaded onto carbon cloth (CC) through facile solvothermal treatment, followed by subsequent single-source pyrolysis. This results in a highly porous 2H-MoS2/CC composite with a sponge-like stacked lamellar morphology. Due to its high porosity and unique nano/microstructure, the MoS2/CC composite exhibits a specific capacitance of 550.0 F g?1at 1 A g?1, outperforming some 1T-MoS2based electrodes. The composite is further assembled into a symmetric all-solid-state supercapacitor, which can be operated stably at a wide potential window and shows a specific capacitance of 127.5 F g?1at 1 A g?1. In addition, the device delivers a high energy density of 70.8 W h kg?1at 1 kW kg?1, which still remains 15.0 W h kg?1at 18.0 kW kg?1. 75% of the performance of the device can be retained after 8000 cycles. Such remarkable electrochemical performance is attributed to its novel nano/microstructures with a large surface area, convenient ion transport pathways, enhanced conductivity, and improved structural stability. Thus, this work demonstrates a highly promising dithiocarbamate-based single-precursor pyrolysis route towards the fabrication of metal sulfides/carbon composites for energy storage applications.

Single-crystal structure and intracellular localization of Zn(II)-thiosemicarbazone complex targeting mitochondrial apoptosis pathways

Chen, Qiu,Fan, Weiwei,Gao, Huashan,Qi, Jinxu,Wang, Fu-An,Wang, Ruiya,Xia, Xichao,Zhao, Wei,Zheng, Yunyun

supporting information, (2020/06/22)

Tracking of drugs in cancer cells is important for basic biology research and therapeutic applications. Therefore, we designed and synthesised a Zn(II)-thiosemicarbazone complex with photoluminescent property for organelle-specific imaging and anti-cancer proliferation. The Zn(AP44eT)(NO3)2 coordination ratio of metal to ligand was 1:1, which was remarkably superior to 2-((3-aminopyridin-2-yl) methylene)-N, N-diethylhydrazinecarbothioamide (AP44eT·HCl) in many aspects, such as fluorescence and anti-tumour activity. Confocal fluorescence imaging showed that the Zn(AP44eT)(NO3)2 was aggregated in mitochondria. Moreover, Zn(AP44eT)(NO3)2 was more effective than the metal-free AP44eT·HCl in shortening the G2 phase in the MCF-7 cell cycle and promoting apoptosis of cancer cells. Supposedly, the effects of these complexes might be located mainly in the mitochondria and activated caspase-3 and 9 proteins.

Process route upstream and downstream products

Process route

sodium O-ethyl dithiocarbonate
140-90-9

sodium O-ethyl dithiocarbonate

C<sub>8</sub>H<sub>15</sub>NOS<sub>4</sub>
327989-09-3

C8H15NOS4

bis-ethoxythiocarbonyldisulfane
502-55-6

bis-ethoxythiocarbonyldisulfane

sodium N,N-diethyldithiocarbamate
148-18-5

sodium N,N-diethyldithiocarbamate

Conditions
Conditions Yield
With sodium nitrate; C8MoN8(3-)*3Na(1+); In water; acetone; at 25 ℃; Rate constant; Equilibrium constant; μ 0.2 mol/l;
carbon disulfide
75-15-0,12122-00-8

carbon disulfide

diethylamine
109-89-7

diethylamine

sodium N,N-diethyldithiocarbamate
148-18-5

sodium N,N-diethyldithiocarbamate

Conditions
Conditions Yield
With sodium hydroxide; In ethanol; water; cooling;
90%
diethylamine; With sodium hydroxide; In methanol; at 20 ℃; for 0.5h;
carbon disulfide;
82%
With sodium hydroxide; In ethanol; at 20 - 40 ℃;
73%
With sodium hydroxide; In water; at 20 ℃; for 1h; Cooling with ice;
69%
With sodium hydroxide; In methanol; other reagent;
With sodium hydroxide; In tetrahydrofuran; water; at 15 - 20 ℃; for 2h;
With sodium hydroxide; In water; Yield given;
With sodium hydroxide;
With sodium hydroxide; In ethanol; for 2h;
With sodium hydroxide; In water; at 20 ℃; for 1h; Cooling with ice;
carbon disulfide; diethylamine; In ethanol; at 5 ℃;
With sodium hydroxide; In ethanol; water;
With sodium hydroxide; pH=Ca. 6.5;
With sodium hydroxide; In ethanol; at 0 ℃;
With sodium hydroxide; In water; ethyl acetate; at 0 - 5 ℃; for 0.5h;
With sodium hydroxide; at 25 ℃; for 5h;
With sodium hydroxide; In methanol; water; at 20 ℃; for 8h; Cooling with ice;
With sodium hydroxide; In ethanol;
With sodium hydroxide; for 4h;
Tributyltin diethyldithiocarbamate
138523-63-4

Tributyltin diethyldithiocarbamate

sodium N,N-diethyldithiocarbamate
148-18-5

sodium N,N-diethyldithiocarbamate

Conditions
Conditions Yield
With sodium hydrogensulfide; In methanol; at 4 ℃;
concentrated NaOH

concentrated NaOH

N-(hydroxyethyl)-ethylenediamine

N-(hydroxyethyl)-ethylenediamine

Diethylene glycol monobutyl ether
112-34-5,9004-77-7

Diethylene glycol monobutyl ether

chlorophene
120-32-1

chlorophene

sodium N,N-diethyldithiocarbamate
148-18-5

sodium N,N-diethyldithiocarbamate

Conditions
Conditions Yield
disulfiram
97-77-8

disulfiram

sodium O-ethyl dithiocarbonate
140-90-9

sodium O-ethyl dithiocarbonate

sodium N,N-diethyldithiocarbamate
148-18-5

sodium N,N-diethyldithiocarbamate

C<sub>8</sub>H<sub>15</sub>NOS<sub>4</sub>
327989-09-3

C8H15NOS4

Conditions
Conditions Yield
With sodium nitrate; C8MoN8(3-)*3Na(1+); In water; acetone; at 25 ℃; Rate constant; Equilibrium constant; μ 0.2 mol/l;
disulfiram
97-77-8

disulfiram

sodium N,N'-diisopropyldithiocarbamate
4092-82-4

sodium N,N'-diisopropyldithiocarbamate

sodium N,N-diethyldithiocarbamate
148-18-5

sodium N,N-diethyldithiocarbamate

C<sub>12</sub>H<sub>24</sub>N<sub>2</sub>S<sub>4</sub>

C12H24N2S4

Conditions
Conditions Yield
With sodium nitrate; potassium hexacyanoferrate(III); In water; acetone; at 25 ℃; Equilibrium constant; μ 0.2 mol/l;
sodium N,N'-diisopropyldithiocarbamate
4092-82-4

sodium N,N'-diisopropyldithiocarbamate

C<sub>12</sub>H<sub>24</sub>N<sub>2</sub>S<sub>4</sub>

C12H24N2S4

tetraisopropylothiuram disulphide
4136-91-8

tetraisopropylothiuram disulphide

sodium N,N-diethyldithiocarbamate
148-18-5

sodium N,N-diethyldithiocarbamate

Conditions
Conditions Yield
With sodium nitrate; potassium hexacyanoferrate(III); In water; acetone; at 25 ℃; Equilibrium constant; μ 0.2 mol/l;
sodium N,N-diethyldithiocarbamate
148-18-5

sodium N,N-diethyldithiocarbamate

Conditions
Conditions Yield
sodium N,N-diethyldithiocarbamate
148-18-5

sodium N,N-diethyldithiocarbamate

2,4-dimethylbenzaldehyde
15764-16-6

2,4-dimethylbenzaldehyde

benzylamine
100-46-9

benzylamine

Conditions
Conditions Yield
With sodium cyanoborohydride; N-ethyl-N,N-diisopropylamine; Pd(PPh3)3; In 4-methyl-morpholine; methanol; CHCl3/AcOH; dichloromethane; ISOPROPYLAMIDE; acetic acid; N,N-dimethyl-formamide;
cadmium(II) nitrate tetrhydrate

cadmium(II) nitrate tetrhydrate

sodium N,N-diethyldithiocarbamate
148-18-5

sodium N,N-diethyldithiocarbamate

bis(N,N-diethyldithiocarbamato)copper(II)
13681-87-3

bis(N,N-diethyldithiocarbamato)copper(II)

Conditions
Conditions Yield
With sodium hydroxide; In methanol; at 0 ℃; for 4h;
79%

Global suppliers and manufacturers

Global( 113) Suppliers
  • Company Name
  • Business Type
  • Contact Tel
  • Emails
  • Main Products
  • Country
  • Wuhan PharmChem Co.,Ltd
  • Business Type:Trading Company
  • Contact Tel:027-85835203
  • Emails:steven@cspharmchem.com
  • Main Products:32
  • Country:China (Mainland)
  • Hangzhou Dingyan Chem Co., Ltd
  • Business Type:Trading Company
  • Contact Tel:86-571-86465881,86-571-87157530,86-571-88025800
  • Emails:sales@dingyanchem.com
  • Main Products:95
  • Country:China (Mainland)
  • Shanghai Upbio Tech Co.,Ltd
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-21-52196435
  • Emails:upbiocn@hotmail.com
  • Main Products:89
  • Country:China (Mainland)
close
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 148-18-5
Post Buying Request Now
close
Remarks: The blank with*must be completed