498-94-2Relevant articles and documents
Electrocatalytic synthesis of isonipecotic acid
Osadchenko,Tomilov
, p. 499 - 500 (2006)
An electrocatalytic synthesis of isonipecotic acid was carried out by cathodic reduction of isonicotinic acid in a membrane electrolyzer on a copper cathode activated with Raney nickel in an alkaline medium under mild conditions. Pleiades Publishing, Inc., 2006.
High-efficiency synthesis method of methyl 4-piperidineacetate
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Paragraph 0030; 0040; 0046; 0050; 0051; 0060; 0070, (2019/01/14)
The invention discloses a high-efficiency synthesis method of methyl 4-piperidineacetate. The high-efficiency synthesis method comprises the following steps: firstly, preparing a colloid; secondly, taking titanium tetrachloride, di-n-octyl ether, cetylamine and carbon disulfide as raw materials to prepare reaction liquid; adding the reaction liquid into the colloid and dropwise adding ammonia water for precipitating to prepare a catalyst; taking 4-picolinic acid as a raw material and preparing 4-nipecotic acid under the reaction of the catalyst; taking the 4-nipecotic acid as the raw materialto prepare the methyl 4-piperidineacetate. The method has the advantages of simple operation, low preparation cost, high yield of a target product and easiness in separation.
Use of Functionalized Onium Salts for Peptide Synthesis
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, (2010/12/18)
A subject of the invention is the use of a salt with a dedicated task of formula (I): [in-line-formulae]A+-L-R—OY, X?[/in-line-formulae] as soluble support for peptide synthesis, in which: X? represents a functional or non-functional anion,Y represents either a hydrogen atom, or a —COOR1 group, R1 representing in particular an alkyl group comprising 1 to 20 carbon atoms,A+ represents a cationic entity,L represents an arm, in particular an alkyl group of 3 to 20 carbon atoms,R represents in particular a group of formula —C(Ra)(Rb)—, Ra and Rb representing independently of one another in particular a hydrogen or an alkyl group, comprising 1 to 20 carbon atoms.
