A DIASTEREOSELECTIVE SYNTHESIS OF (S,S)-α-FLUORO-2,2-DIMETHYL-1,3-DIOXOLANE-4-PROPANOIC ACID METHYL ESTER, A KEY INTERMEDIATE FOR THE PREPARATION OF ANTI-HIV EFFECTIVE FLUORODIDEOXYNUCLEOSIDES

DOI: 10.1016/S0040-4039(00)76880-8

Source and publish data:

Tetrahedron Letters p. 3263 - 3266 (1994)

Update date:2022-08-05

Topics:

Authors:

Siddiqui, Maqbool A.

Marquez, Victor E.

Driscoll, John S.

Barchi, Joseph J. Jr.

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Article abstract of DOI:10.1016/S0040-4039(00)76880-8

(S,S)-α-fluoro-2,2-dimethyl-1,3-dioxolane-4-propanoic acid methyl ester (10), a key intermediate for the preparation of anti-HIV active 9-(2,3-dideoxy-2-fluoro-β-D-threo-pentafuranosyl)-adenine (1, FddA) and 1-(2,3-dideoxy-2-fluoro-β-D-threo-pentofuranosy

Full text of DOI:10.1016/S0040-4039(00)76880-8

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