Synthesis of nectrisine and related compounds, and their biological evaluation

DOI: 10.1016/S0040-4020(99)00459-7

Source and publish data:

Tetrahedron p. 8353 - 8364 (1999)

Update date:2022-08-03

Topics:

Authors:

Kim, Yong Jip

Takatsuki, Akira

Kogoshi, Naoto

Kitahara, Takeshi

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Article abstract of DOI:10.1016/S0040-4020(99)00459-7

An efficient and novel process is described for the synthesis of nectrisine 5 and its related derivatives 6,7 as potent glucosidase inhibitors via the corresponding lactams starting from D-(-)-diethyl tartrate. Also the results of biological evaluation of the synthesized compounds are described.

Full text of DOI:10.1016/S0040-4020(99)00459-7

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