Bioorganic and Medicinal Chemistry Letters p. 1261 - 1266 (1997)
Update date:2022-08-03
Topics:
Lee, Byung H.
Clothier, Michael F.
The C26 dimethyl dioxepinoindole ring found in marcfortine A is unique among natural products. In order to ascertain the importance of the dimethyl moiety to anthelmintic activity, we prepared a variety of C26-dialkyl and spiroalkyl analogs. They include cyclobutyl, cyclohexyl, diethyl, and ethyl-methyl derivatives. This communication describes the synthesis of these compounds.
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(1997)
