
Journal of Heterocyclic Chemistry p. 919 - 923 (1983)
Update date:2022-08-05
Topics:
Vekemans
Pollers Wieers
Hoornaert
The hydrohalides of 2-sec-aminoalkanenitriles on treatment with oxalyl halides in o-dichlorobenzene at 80-100° give 3,5-dihalo-2(1H)-pyrazinones, of which the 3-halo substituent is easily replaced by nucleophiles. A reaction mechanism for the pyrazinone s
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