Synthesis of substituted N-arylpiperidines via organobismuth derivatives

Article abstract of DOI:10.1055/s-1994-25569

The synthesis of N-arylpiperidines functionalized both on the aromatic and piperidine ring was performed using conveniently substituted triarylbismuthine derivatives as arylating agents. This method is, in particular, indicated to arylate the nitrogen atom of a secondary amine with a phenyl ring bearing electron-withdrawing groups in the m-position.