Tetrahedron Letters p. 3885 - 3888 (1997)
Update date:2022-08-11
Topics:
Kieburg, Christoffer
Lindhorst, Thisbe K.
Oligoantennary neoglycoconjugates can act as powerful inhibitors of carbohydrate-protein interactions and thus serve as antiadhesives in carbohydrate-based adhesion systems. They were obtained by a procedure that doesn't require protecting groups. Various unprotected NCS-functionalized saccharides were coupled with oligoamines in aqueous solution. This versatile method is generally applicable to the synthesis of thiourea-bridged glycodendrimers.
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