T+:Very toxic;
918-00-3Relevant academic research and scientific papers
1,1,1-trichloroacetone preparation method
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Paragraph 0037-0044, (2020/03/12)
The invention provides a 1,1,1-trichloroacetone preparation method, which comprises the following steps: 1, adding monochloroacetone and an alkaline compound into a large amount of an aqueous solutionwithout other organic solvents; 2, forming an aqueous solution or a turbid liquid from the alkaline compound in water while stirring; 3, introducing chlorine gas while stirring until the solution isclear; and 4, in the whole reaction process, controlling the temperature at 0-25 DEG C. According to the invention, the method is simple in process, convenient to operate, high in yield and convenientfor industrial production, and can effectively control the acetone chlorination position, so that the generation of byproducts such as 1,1,3-trichloroacetone, tetrachloroacetone, pentachloroacetone and the like is reduced, and the purity of the prepared product is high and can reach more than 85% without further purification.
Kinetics and mechanistic investigation into the degradation of naproxen by a UV/chlorine process
Gao, Yu-Qiong,Gao, Nai-Yun,Chu, Wen-Hai,Yang, Qin-Lin,Yin, Da-Qiang
, p. 33627 - 33634 (2017/07/12)
In this study, UV irradiation combined with chlorine (UV/chlorine) was used to degrade naproxen (NPX), a typical non-steroidal anti-inflammatory drug (NSAID) widely used for the treatment of symptoms associated with inflammation, in water. Compared with UV irradiation alone and direct chlorination, the UV/chlorine process shows a synergistic effect on NPX degradation. The effects of different factors, including the chlorine dose, solution pH, and the presence of Cl-, HCO3- or humic acid (HA), on NPX degradation in the UV/chlorine process were investigated. The results indicated that the degradation of NPX followed pseudo-first-order kinetics in all cases, and the rate constant increased as the chlorine dose increased and decreased as the pH increased. The effects of the water matrix on UV/chlorine treatment were species-dependent. The NPX degradation rate was inhibited by the presence of HCO3- and HA but significantly improved by Cl-. LC/MS/MS analysis indicated that NPX decomposition in the UV/chlorine process was associated with decarboxylation, demethylation and hydroxylation. These results indicate that the UV/chlorine process is a promising technology for the treatment of water polluted by emerging contaminants, such as NPX. However, UV/chlorine can notably enhance the formation of disinfection by-products compared to direct chlorination, which should be carefully considered when integrating this process into drinking water treatment schemes.
Selected Methods for the Oxidation of 1,1,1-Trichloro-2-alkanols. An Efficient Modification Using Chromic Acid
Gallina, Carlo,Giordano, Cesare
, p. 466 - 468 (2007/10/02)
The effectiveness of thirteen largely applied procedures has been checked in the oxidation of 1,1,1-trichloropropan-2-ol.A new, simple, and efficient modification using chromic acid has been found for the preparation of representative trichloromethyl ketones.
1,1,1-TRICHLOROPROPANONE: A MILD, SELECTIVE ACETYLATING AGENT
Salim, Jose Roberto,Nome, Faruk,Rezende, Marcos Caroli
, p. 1181 - 1188 (2007/10/02)
The use of the title compound in the acetylation of primary and secondary amines is described.
TRICHLOROMETHYLATION OF CARBONYL COMPOUNDS IN THE PRESENCE OF CROWN ETHERS
Kyazimov, A. S.,Abdullabekov, I. M.,Karaev, S. F.
, p. 1456 - 1458 (2007/10/02)
The reaction of potassium trichloroacetate with carbonyl compounds (aldehydes, acid anhydrides and chlorides) in acetonitrile in the presence of crown ethers leads to an increase of 11-19percent in the yield of the C-trichloromethylation products and reduces the reaction time by an order of magnitude.The macrocyclic perhydrodibenzo-18-crown-6-polyether, used as phase-transfer catalyst, is more effective than dibenzo-18-crown-6.
SYNTHESIS OF SOME TRIS(TRIMETHYLSILYL)GERMYL COMPOUNDS
Brook, A. G.,Abdesaken, F.,Soellradl, H.
, p. 9 - 14 (2007/10/02)
A variety of compounds containing the tris(trimethylsilyl)germyl group were prepared and characterized spectroscopically.Photolysis of adamantoyltris(trimethylsilyl)germane failed to yield the isomeric germene: in CCl4 the photolysis appeared to occur by a Norrish type 1 process.
CH3(.) vs. CF3(.): Relative Rates of Formation from β-Scission
Jiang, Xi-Kui,Li, Xing-Ya,Wang, Ke-Yang
, p. 745 - 746 (2007/10/02)
The relative rates of formation of CH3(.) and CF3(.) from β-scission reactions of trifluoro-t-butoxy radical (1) have been measured to be about 10:1 by thermolysing both trifluoro-t-butyl hypochlorite (4) and bis(trifluoro-t-butyl) peroxydicarbonate (14) in CCl4 at 160 and 140 deg C.
Generation and Chemical Properties of Dicyclopropylcarbene. Ring Expansion, Chlorine Abstraction, C-H Insertion, and Alkene Addition Reactions
Bekhazi, Michel,Risbood, Prabhakar A.,Warkentin, John
, p. 5675 - 5679 (2007/10/02)
Thermolysis of 5,5-dicyclopropyl-2-methoxy-2-methyl-Δ3-1,3,4-oxadiazoline in solution at 80 deg C affords dicycloproylcarbene and methyl acetate in high yields.Dicyclopropylcarbene undergoes a variety of reactions including ring expansion to 1-cyclopropylcyclobutene, chlorine atom abstraction from carbon tetrachloride, and efficient insertion into the CH bond of chloroform.A rationale for the very different reactions of the carbene with CCl4 and CHCl3 is suggested.Carbene trapping by addition to tetrachloroethylene, using the oxadiazoline as the carbene source, is illustrated with the preparation of an adduct.
