127-08-2 Usage
Description
Different sources of media describe the Description of 127-08-2 differently. You can refer to the following data:
1. Potassium acetate is the potassium salt of acetic acid. It is manufactured through the reaction between a potassium base such as potassium hydroxide or potassium carbonate with acetic acid. It is an important macromineral with many physiological functions and is required for nerve conduction, cardiac, skeletal and smooth muscle contraction, energy generation, nucleic acid synthesis as well as mainlining the blood pressure and normal renal function. It can be taken as a nutritional supplement with antihypertensive effects and prevention effects against hypokalemia. It has several other common applications: (1) as a deicer; (2) as a food additive; (3) molecular biology applications such as DNA purification, tissue preservation, fixation and mummification; (4) Death penalty (5) as the catalyst during the production of polyurethanes.
2. Potassium acetate (CH3CO2K) is the potassium salt of acetic acid.
References
https://pubchem.ncbi.nlm.nih.gov/compound/Potassium_acetate#section=Top
https://en.wikipedia.org/wiki/Potassium_acetate
Chemical Properties
Different sources of media describe the Chemical Properties of 127-08-2 differently. You can refer to the following data:
1. Potassium acetate, KC2H302, is a white, deliquescent solid, soluble in water and alcohol, insoluble in ether, that melts at 292°C. It is used as an analytical reagent, dehydrating agent, in medicine, and in crystal glass manufacture.
2. Pure potassium acetate is odorless or has a faint acetic odor and a saline taste.
Uses
Different sources of media describe the Uses of 127-08-2 differently. You can refer to the following data:
1. 1) Potassium acetate, crystalline powder, USP is, as its name suggests, the potassium salt of acetic acid and is used as a catalyst for producing polyurethanes2) In the food industry it is used as a food additive, an acidity regulator and a preservative
2. Used as buffers.
3. Potassium acetate is used in the manufacture of glass; as a softening agent for papers and textiles; as a dehydrating agent; and as a buffer. In medicine it is used as an expectorant and diuretic.
4. Potassium acetate was originally used in the preparation of Cadet's fuming liquid, the first organometallic compound produced. It is used as diuretic and urinary alkaliser, and acts by changing the physical properties of the body fluids and by functioning as an alkali after absortion.
Application
Potassium acetate is used as a catalyst in the production of polyurethanes.Potassium acetate can be used as a deicer instead of chloride salts such as calcium chloride or magnesium chloride. It offers the advantage of being less aggressive on soils and much less corrosive, and for this reason is preferred for airport runways. It is, however, more expensive. Potassium acetate is also the extinguishing agent used in class K fire extinguishers because of its ability to cool and form a crust over burning oils.3 – 1 - Food additive Potassium acetate is used as a food additive as a preservative and acidity regulator. In the European Union, it is labeled by the E number E261 ; it is also approved for usage in the USA and Australia and New Zealand. Potassium diacetate (CAS # 4251-29-0) with formula KH(O2CCH3)2 is a related food additive with the same E number as potassium acetate. 3 – 2 - Medicine and biochemistry In medicine, potassium acetate is used as part of replacement protocols in the treatment of diabetic ketoacidosis because of its ability to break down into bicarbonate and help neutralize the acidotic state. In molecular biology, potassium acetate is used to precipitate dodecyl sulfate (DS) and DS-bound proteins, allowing the removal of proteins from DNA. It is also used as a salt for the ethanol precipitation of DNA.
Preparation
Different sources of media describe the Preparation of 127-08-2 differently. You can refer to the following data:
1. Potassium Acetate can be prepared by treating a potassium-containing base such as potassium hydroxide or potassium carbonate with acetic acid: 2 CH3COOH + K2CO3→ 2 CH3CO2K + CO2 + H2O This sort of reaction is known as an acid-base neutralization reaction. Potassium acetate is the salt that forms along with water as acetic acid and potassium hydroxide are neutralized together. Conditions/substances to avoid are: moisture, heat, flames, ignition sources, and strong oxidizing agents.
2. Potassium acetate is prepared by addition of potassium carbonate in a small volume of water to acetic acid solution, followed by evaporation and crystallization:
K2CO3+ 2CH3COOH →2CH3COOK + H2O
Definition
ChEBI: A potassium salt comprising equal numbers of potassium and acetate ions
General Description
Potassium acetate is generally used as an acidity regulator, buffer, preservative and firming agent.
Flammability and Explosibility
Nonflammable
Check Digit Verification of cas no
The CAS Registry Mumber 127-08-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 127-08:
(5*1)+(4*2)+(3*7)+(2*0)+(1*8)=42
42 % 10 = 2
So 127-08-2 is a valid CAS Registry Number.
InChI:InChI=1/C2H4O2.K/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1
127-08-2Relevant articles and documents
Kinetic challenges facing oxalate, malonate, acetoacetate, and oxaloacetate decarboxylases
Wolfenden, Richard,Lewis, Charles A.,Yuan, Yang
, p. 5683 - 5685 (2011)
To compare the powers of the corresponding enzymes as catalysts, the rates of uncatalyzed decarboxylation of several aliphatic acids (oxalate, malonate, acetoacetate, and oxaloacetate) were determined at elevated temperatures and extrapolated to 25 °C. In the extreme case of oxalate, the rate of the uncatalyzed reaction at pH 4.2 was 1.1 × 10-12 s-1, implying a 2.5 × 1013-fold rate enhancement by oxalate decarboxylase. Whereas the enzymatic decarboxylation of oxalate requires O 2 and MnII, the uncatalyzed reaction is unaffected by the presence of these cofactors and appears to proceed by heterolytic elimination of CO2.
Research and development of method for potassium acetate of high purity
Fakeev,Murskii,Krasil'Shchik
, p. 1807 - 1813 (2012)
Crystallization of potassium acetate from aqueous solutions, an effect of product yield and washing of its crystals on an efficiency of purification were investigated. Behavior of KCH3COO·1.5H2O was studied in heating. Based on data of the study a technological scheme of producing anhydrous potassium acetate of high purity was developed.
Catalytic oxidation of soot over alkaline niobates
Pecchi,Cabrera,Buljan,Delgado,Gordon,Jimenez
, p. 255 - 261 (2013)
The lack of studies in the current literature about the assessment of alkaline niobates as catalysts for soot oxidation has motivated this research. In this study, the synthesis, characterization and assessment of alkaline metal niobates as catalysts for soot combustion are reported. The solids MNbO 3 (M = Li, Na, K, Rb) are synthesized by a citrate method, calcined at 450 °C, 550 °C, 650 °C, 750 °C, and characterized by AAS, N2 adsorption, XRD, O2-TPD, FTIR and SEM. All the alkaline niobates show catalytic activity for soot combustion, and the activity depends basically on the nature of the alkaline metal and the calcination temperature. The highest catalytic activity, expressed as the temperature at which combustion of carbon black occurs at the maximum rate, is shown by KNbO3 calcined at 650 °C. At this calcination temperature, the catalytic activity follows an order dependent on the atomic number, namely: KNbO3 > NaNbO3 > LiNbO3. The RbNbO3 solid do not follow this trend presumably due to the perovskite structure was not reached. The highest catalytic activity shown by of KNbO3, despite the lower apparent activation energy of NaNbO3, stress the importance of the metal nature and suggests the hypothesis that K+ ions are the active sites for soot combustion. It must be pointed out that alkaline niobate subjected to consecutive soot combustion cycles does not show deactivation by metal loss, due to the stabilization of the alkaline metal inside the perovskite structure.
Fry, H. S.,Otto, E.
, p. 1122 (1928)
Bereman, Robert D.,Baird, Donald M.,Moreland, Charles G.
, p. 59 - 62 (1983)
Cobalt-Catalyzed Acceptorless Dehydrogenation of Alcohols to Carboxylate Salts and Hydrogen
Gunanathan, Chidambaram,Kishore, Jugal,Pattanaik, Sandip,Pradhan, Deepak Ranjan
supporting information, (2020/03/03)
The facile oxidation of alcohols to carboxylate salts and H2 is achieved using a simple and readily accessible cobalt pincer catalyst (NNNHtBuCoBr2). The reaction follows an acceptorless dehydrogenation pathway and displays good functional group tolerance. The amine-amide metal-ligand cooperation in cobalt catalyst is suggested to facilitate this transformation. The mechanistic studies indicate that in-situ-formed aldehydes react with a base through a Cannizzaro-type pathway, resulting in potassium hemiacetolate, which further undergoes catalytic dehydrogenation to provide the carboxylate salts and H2