941-98-0Relevant articles and documents
Copper-Catalyzed Alkynylation of Benzylic C-H Bonds with Alkynylboronic Esters
Buendia, Mikkel B.,Balin, Jan-Georges J.,Andersen, Mette E.,Lian, Zhong,Kramer, Soren
supporting information, p. 150 - 154 (2021/04/23)
We report a simple method for copper-catalyzed benzylic C-H alkynylation that uses alkynylboronic esters as nucleophilic coupling partners. The catalytic system is readily available and the reaction takes place under mild conditions. Different substrates for the C-H functionalization, as well as various alkynylboronic ester nucleophiles, were evaluated. Finally, three examples of enantioselective C-H alkynylations are presented.
Visible light-mediated, high-efficiency oxidation of benzyl to acetophenone catalyzed by fluorescein
Geng, Haoxing,Liu, Xin,Zhu, Qing
supporting information, (2021/12/20)
An environmentally friendly aerobic oxidation of benzyl C(sp3)-H bonds to ketones via selective oxidation catalysis was developed. Fluorescein is an efficient photocatalyst with excellent chemical selectivity. The reaction has a wide substrate scope, and a successful gram-scale experiment demonstrated its potential industrial utility.
Hydration of Alkynes to Ketones with an Efficient and Practical Polyoxomolybdate-based Cobalt Catalyst
Xie, Ya,Wang, Jingjing,Wang, Yunyun,Han, Sheng,Yu, Han
, p. 4985 - 4989 (2021/10/12)
Hydration of alkynes to ketones is one of the most atom economical and universal methods for the synthesis of carbonyl compounds. However, the basic reaction usually requires organic ligand catalysts or harsh reaction conditions to insert oxygen into the C≡C bond. Here, we report an inorganic ligand supported cobalt (III) catalyst, (NH4)3[CoMo6O18(OH)6], which is supported by a central cobalt (III) mononucleus and a ring-shaped pure inorganic ligand composed of six MoVIO6 octahedrons to avoid the disadvantages of expensive and unrecyclable organic ligand catalysts or noble metal catalysts. Under mild conditions, the cobalt (III) catalyst can be used for the hydration of alkynes to ketones. The catalyst is non-toxic, green, and environment friendly. The catalyst can be recycled at least six times with high activity. According to control experiments, a reasonable mechanism is provided.