Condensation of Conjugated Enones With Diethyl Aminomalonate: A New and Convenient Access to 2,2-Bis(ethoxycarbonyl)-3,4-dihydro-2H-pyrroles

DOI: 10.1055/s-1987-27941

Source and publish data:

Synthesis p. 353 - 357 (1987)

Update date:2022-08-03

Topics:

Authors:

Itoua, Gaston Bedel

Laronze, Jean-Yves

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Article abstract of DOI:10.1055/s-1987-27941

2,2-Bis-(ethoxycarbonyl)-3,4-dihydro-2H-pyrroles are prepared from conjugated enones and diethyl aminomalonate by a one-step cyclocondensation reaction.Reduction of the products with sodium cyanoborohydride affords the corresponding pyrrolidines.

Full text of DOI:10.1055/s-1987-27941

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