Tetrahedron Letters p. 7197 - 7200 (1990)
Update date:2022-08-05
Topics:
Sugiyama
Hosoda
Saito
Asai
Saito
Alkylation of d(CGTATACG) by antitumor antibiotic duocarmycin A was investigated. It was found that N3 of adenine6 (A6) attacks the cyclopropane subunit of duocarmycin A to produce covalently alkylated adduct 5. Upon heating (90 °C, 5 min) the adduct 5 decomposed to modified oligomer 1 with concomitant release of adenine adduct 2.
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Doi:10.1016/j.tetlet.2005.06.026
(2005)Doi:10.1016/j.molstruc.2014.01.010
(2014)Doi:10.1016/j.phytochem.2005.04.027
(2005)Doi:10.1002/anie.201801462
(2018)Doi:10.1002/hlca.19570400223
(1957)Doi:10.1039/j19690000565
(1969)
