1873-88-7

Basic information

• Product Name: Bis(trimethylsiloxy)methylsilane
• Synonyms: 1,1,1,3,5,5,5-heptamethyl-trisiloxan;3H-Heptamethyltrisiloxane;1,1,1,3,5,5,5-HEPTAMETHYLTRISILOXANE;BIS(TRIMETHYLSILOXY)METHYLSILANE;DOW CORNING 1107 WATER REPELLENT AND POWDER TREATMENT;1,1,1,3,5,5,5-HEPTAMETHYLTRISILOXANE, 97 %;40M25);40M40,commercialgrade
• CAS NO: 1873-88-7
• Molecular Formula: C₇H₂₂O₂Si₃
• Molecular Weight: 222.5
• EINECS: 217-496-1
• Product Categories: Industrial/Fine Chemicals;Si (Classes of Silicon Compounds);Siloxanes;Si-O Compounds;Organometallic Reagents;Organosilicon
• Mol File: 1873-88-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: <0°C
• Boiling Point: 142 °C(lit.)
• Flash Point: 82 °F
• Appearance: Colourless liquid
• Density: 0.819 g/mL at 25 °C(lit.)
• Vapor Pressure: 8.5hPa at 25℃
• Refractive Index: n20/D 1.382(lit.)
• Storage Temp.: 15-25°C
• Water Solubility: Miscible with acetone, ethanol, diethyl ether. Insoluble in water.
• Stability: Stable. Flammable. Incompatible with strong oxidizing agents.
• BRN: 1748455
• CAS DataBase Reference: Bis(trimethylsiloxy)methylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: Bis(trimethylsiloxy)methylsilane(1873-88-7)
• EPA Substance Registry System: Bis(trimethylsiloxy)methylsilane(1873-88-7)

Safety Data

• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 26-36
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 3
• F: 10-21
• TSCA: Yes
• HazardClass: 3
• PackingGroup: II
• Hazardous Substances Data: 1873-88-7(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 1873-88-7 differently. You can refer to the following data:
1. Heptamethyltrisiloxane is used to catalyze reduction reactions in organic syntheses.
2. 1,1,1,3,5,5,5-Heptamethyltrisiloxane is a Basic material for synthetic polyalkyleneoxide modified heptamethyltrisiloxane which is a kind of specific structure surfactant for pesticide additives, coating additives, etc.
3. Bis(trimethylsiloxy)methylsilane is an important raw material and intermediate used in organic synthesis, pharmaceutical and dyestuff.
4. 1,1,1,3,5,5,5-Heptamethyltrisiloxane can be used for the aromatic C-H silylation of arenes in the presence of a platinum complex catalyst.It can also be used as a reagent to synthesize: 3-Octyl-1,1,1,3,5,5,5-heptamethyltrisiloxane, an agricultural adjuvant and sensory performance enhancer used in cosmetic formulations.Isoindigo-based conjugated polymer with siloxane-terminated solubilizing group.Monosiloxy esters with a variety of acids.

Description

Bis (trimethylsiloxy) methylsilane acts as an important raw material and intermediate used in organic synthesis, pharmaceutical and dyestuff. For example, it can be used for the platinum-catalyzed aromatic C-H silylation of arenes. It can also be used for the silylation of aryl iodides.

Chemical Properties

colourless liquid

Flammability and Explosibility

Flammable

References

https://www.alfa.com/zh-cn/catalog/H60586/ Murata, Miki, et al. "Silylation of Aryl Iodides with 1,1,1,3,5,5,5 -Heptamethyltrisiloxane Catalyzed by Transition-Metal Complexes." Synlett 2007.09(2007):1387-1390. Murata, Miki, et al. "Platinum-Catalyzed Aromatic C—H Silylation of Arenes with 1,1,1,3,5,5,5-Heptamethyltrisiloxane." Cheminform38.50 (2007):no-no.

InChI:InChI=1/C7H21O2Si3/c1-10(8-11(2,3)4)9-12(5,6)7/h1-7H3

Synthetic route

Dichloromethylsilane (75-54-7) + chloro-trimethyl-silane (75-77-4) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7)

Conditions	Yield
With Methamphetamin In diethyl ether for 1h;	68%
With water

Dichloromethylsilane (75-54-7) + sodium trimethylsilanolate (18027-10-6) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7)

Conditions	Yield
In diethyl ether for 10h; Heating;	59%

Dichloromethylsilane (75-54-7) + Trimethylsilanol (1066-40-6) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7)

Conditions	Yield
With pyridine In hexane at -30 - 20℃; for 16h;	34%

bis(trimethylsiloxy)(trimethylsilyl)methylsilane (99532-16-8) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + Octamethyltrisiloxane (107-51-7)

Conditions	Yield
at 850℃;	A 14% B 10%

Dichloromethylsilane (75-54-7) + Hexamethyldisiloxane (107-46-0) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7)

Conditions	Yield
In hexane

Hexamethyldisiloxane (107-46-0) + 1,3,5,7,9-pentamethylcyclopentasiloxane (6166-86-5) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7)

Dichloromethylsilane (75-54-7) + chloro-trimethyl-silane (75-77-4) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + 1,1,1,3,5,7,7,7-octamethyltetrasiloxane (16066-09-4) + 2,4,6,8-tetramethylcyclotetrasiloxane (2370-88-9) + 1,1,1,3,5,7,9,9,9-nonamethyl-pentasiloxane (17478-13-6) + 1,3,5,7,9-pentamethylcyclopentasiloxane (6166-86-5) + polymethylhydrosiloxane (17998-54-8)

Conditions	Yield
With water In toluene at 20℃; for 27h; Product distribution; hydrolytic copolycondensation depending on final concentration of hydrochloric acid; other dialkyldichlorosilanes;	A n/a B 6 % Chromat. C 4 % Chromat. D 3.5 % Chromat. E 3 % Chromat. F 2.0 % Chromat.

Dichloromethylsilane (75-54-7) + chloro-trimethyl-silane (75-77-4) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7)

Conditions	Yield
With Methamphetamin In diethyl ether for 1h;	68%
With water

Dichloromethylsilane (75-54-7) + sodium trimethylsilanolate (18027-10-6) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7)

Conditions	Yield
In diethyl ether for 10h; Heating;	59%

Dichloromethylsilane (75-54-7) + Trimethylsilanol (1066-40-6) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7)

Conditions	Yield
With pyridine In hexane at -30 - 20℃; for 16h;	34%

bis(trimethylsiloxy)(trimethylsilyl)methylsilane (99532-16-8) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + Octamethyltrisiloxane (107-51-7)

Conditions	Yield
at 850℃;	A 14% B 10%

Dichloromethylsilane (75-54-7) + Hexamethyldisiloxane (107-46-0) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7)

Conditions	Yield
In hexane

Hexamethyldisiloxane (107-46-0) + 1,3,5,7,9-pentamethylcyclopentasiloxane (6166-86-5) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7)

Dichloromethylsilane (75-54-7) + chloro-trimethyl-silane (75-77-4) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + 1,1,1,3,5,7,7,7-octamethyltetrasiloxane (16066-09-4) + 2,4,6,8-tetramethylcyclotetrasiloxane (2370-88-9) + 1,1,1,3,5,7,9,9,9-nonamethyl-pentasiloxane (17478-13-6) + 1,3,5,7,9-pentamethylcyclopentasiloxane (6166-86-5) + polymethylhydrosiloxane (17998-54-8)

Conditions	Yield
With water In toluene at 20℃; for 27h; Product distribution; hydrolytic copolycondensation depending on final concentration of hydrochloric acid; other dialkyldichlorosilanes;	A n/a B 6 % Chromat. C 4 % Chromat. D 3.5 % Chromat. E 3 % Chromat. F 2.0 % Chromat.

Dichloromethylsilane (75-54-7) + chloro-trimethyl-silane (75-77-4) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + 1,1,1,3,5,7,7,7-octamethyltetrasiloxane (16066-09-4) + 2,4,6,8-tetramethylcyclotetrasiloxane (2370-88-9) + 1,3,5,7,9-pentamethylcyclopentasiloxane (6166-86-5)

Conditions	Yield
With water In toluene at 20℃; for 27h; Further byproducts given;	A 21 % Chromat. B n/a C 3 % Chromat. D 1.5 % Chromat.

1,1,1,3,3-pentamethyl-1,3-disiloxane (1438-82-0) → Hexamethyldisiloxane (107-46-0) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + Octamethyltrisiloxane (107-51-7) + decamethyltetrasiloxane (141-62-8) + 1,1,1,3,3,5,5-heptamethyltrisiloxane (2895-07-0) + M2DDH (77606-50-9)

Conditions	Yield
With bis(triphenylphosphine)carbonyliridium(I) chloride In benzene at 70℃; for 116h; Product distribution; other siloxanes;

Dichloromethylsilane (75-54-7) + hexane (110-54-3) + Hexamethyldisiloxane (107-46-0) + ice → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + 1,1,1,3,5,7,7,7-octamethyltetrasiloxane (16066-09-4) + 1,1,1,3,5,7,9,9,9-nonamethyl-pentasiloxane (17478-13-6) + polymethylhydrosiloxane (17998-54-8)

Conditions	Yield
Behandeln des Reaktionsprodukts mit konz.H2SO4; Produkt 5: Tris-trimethylsiloxy-methyl-silan;

Hexamethyldisiloxane (107-46-0) + poly(hydrogenmethyl)siloxan → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7)

Conditions	Yield
With Lewatit SPC 118 at 90℃; for 4h;

Dichloromethylsilane (75-54-7) + Hexamethyldisiloxane (107-46-0) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + 1.1.1.3.5.7.7.7-octamethyl-tetrasiloxane and 1.1.1.3.5.7.9.9.9-nonamethyl-pentasiloxane and 1.1.1.3.5.7.9.11.11.11-decamethyl-hexasiloxane

Conditions	Yield
With hexane; Methamphetamin Behandlung des Reaktionsprodukts mit konz.H2SO4;

Dichloromethylsilane (75-54-7) + Hexamethyldisiloxane (107-46-0) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + 1,1,1,3,5,7,7,7-octamethyltetrasiloxane (16066-09-4) + 1,1,1,3,5,7,9,9,9-nonamethyl-pentasiloxane (17478-13-6) + polymethylhydrosiloxane (17998-54-8)

Conditions	Yield
With H2O In hexane; water addn. of (CH3)HSiCl2 to ice, (CH3)3SiOSi(CH3)3 and hexane; stirring of the mixt. with concd. H2SO4 at room temp. for 2 h;;
With water In hexane; water addn. of (CH3)HSiCl2 to ice, (CH3)3SiOSi(CH3)3 and hexane; stirring of the mixt. with concd. H2SO4 at room temp. for 2 h;;
With H2O In hexane; water addn. of (CH3)HSiCl2 to ice, (CH3)3SiOSi(CH3)3 and hexane; stirring of the mixt. with concd. H2SO4 at room temp. for 2 h;;

methylsilane (992-94-9) + Hexamethyldisiloxane (107-46-0) → 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7)

Conditions	Yield
With sulfuric acid at 20℃; for 4h;

oct-1-ene (111-66-0) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → 3-n-octyl-1,1,1,3,5,5,5-heptamethyltrisiloxane (17955-88-3)

Conditions	Yield
With tetradecyl(tributyl)phosphonium bis(trifluoromethylsulfonyl)amide; C24H20Cl2P2Pt at 100℃; for 1h; Reagent/catalyst;	100%
With tetradecyl(tributyl)phosphonium bis(trifluoromethylsulfonyl)amide; bis(cyclooctadiene (μ-silyloxytrimethyl) rhodium(I)) at 110℃; for 1h; Catalytic behavior; Reagent/catalyst; Time;	100%
With nickel 2-ethylhexanoate; 1,4-bis(2,6-diisopropylphenyl)-2,3-dimethyl-1,4-diazabuta-1,3-diene In neat (no solvent) at 23℃; for 6h; regioselective reaction;	99%

1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + Tetraethylene Glycol Mono-2-methylallyl Ether (78827-93-7) → C19H46O7Si3

Conditions	Yield
platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex at 80 - 85℃; Inert atmosphere; Sodium propionate buffer;	100%

1-hexene (592-41-6) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → 3-n-hexyl-1,1,1,3,5,5,5-heptamethyltrisiloxane (1873-90-1)

Conditions	Yield
With 1,3-bis(tert-buthylethynyl)-1,1,3,3-tetramethyldisiloxane platinum (0) at 50℃; for 16h; Time; Reagent/catalyst;	100%
With C27H55NOPtSi5 In benzene-d6; toluene at 50℃; for 5h; Reagent/catalyst; Concentration; Schlenk technique; Inert atmosphere;	95%
With C24H33N2ORh In tetrahydrofuran at 20℃; for 24h; Time; Inert atmosphere; Glovebox; regioselective reaction;	86%

1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + methylbis(trimethylsilyloxy)vinylsilane (5356-85-4) → C16H44O4Si6 (31576-63-3)

Conditions	Yield
With [Fe(CO)3{(H2C=CHSiMe2O)3SiMe}] at 20℃; for 20h; Catalytic behavior; Reagent/catalyst; Time; Temperature; Concentration; Inert atmosphere; Schlenk technique;	100%
With [Fe(CO)3{(H2C=CHSiMe2)2O}] In decane; toluene at 80℃; for 0.166667h; Reagent/catalyst; Inert atmosphere;	100%

1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + phenylacetylene (536-74-3) → (E)-1,1,1,3,5,5,5-heptamethyl-3-styryltrisiloxane (198623-99-3)

Conditions	Yield
With C24H23ClCrIrNO3 In 1,1,2,2-tetrachloroethane at 60℃; for 40h; Catalytic behavior; Inert atmosphere; Schlenk technique; regioselective reaction;	100%

1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + thiophene-2-sulfonic acid tert-butylamide (100342-30-1) → C15H33NO4S2Si3

Conditions	Yield
With norborn-2-ene; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 2.9-dimethyl-1,10-phenanthroline In tetrahydrofuran at 100℃; for 6h; Inert atmosphere; Sealed tube; regioselective reaction;	100%

3-phenylfuran (13679-41-9) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → C17H28O3Si3

Conditions	Yield
Stage #1: 1,1,1,3,5,5,5-heptamethyltrisiloxan With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; C25H35N3; cyclohexene In tetrahydrofuran Inert atmosphere; Glovebox; Stage #2: 3-phenylfuran In tetrahydrofuran at 65℃; for 16h; Reagent/catalyst; Sealed tube; Inert atmosphere; regioselective reaction;	100%

1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + 8-(allyloxyl)-1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorooctane (103628-86-0) → 3-(propenyloxy-1H,1H,2H,2H-perfluorooctyl)-1,1,1,3,5,5,5-heptamethyltrisiloxane

Conditions	Yield
With dichloro(1,5-cyclooctadiene)platinum(ll) In dichloromethane; toluene at 82℃; for 24h;	99%

1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → hydrogen (1333-74-0)

Conditions	Yield
With [Ir(H)(cis-cyclooctene)(CF3SO3)(bis(pyridine-2-yloxy)methylsilyl)]; water In neat (no solvent) at 20℃; Catalytic behavior;	99%
With TiO2 In tert-butyl alcohol Kinetics; 323 K;
With TiO2 In further solvent(s) Kinetics; 323 K, solvent was 2-butoxyethanol;
With TiO2 In isopropyl alcohol Kinetics; 323 K;

ethene (74-85-1) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → 3-ethyl-1,1,1,3,5,5,5-heptamethyltrisiloxane (17861-60-8)

Conditions	Yield
With C22H34FeO2Si4 In toluene at 20℃; for 16h; Inert atmosphere; Schlenk technique;	99%
With C21H34FeO2Si4 In toluene at 20℃; under 760.051 Torr; for 5h; Schlenk technique;	93%

1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → 1,1,1,3,5,5,5-heptamethyltrisiloxan-3-ole (5272-21-9) + hydrogen (1333-74-0)

Conditions	Yield
With [Ir(H)(cis-cyclooctene)(CF3SO3)(bis(pyridine-2-yloxy)methylsilyl)]; water In dichloromethane at 20℃; Catalytic behavior;	A 99% B 1 mmol

3-chlorothiophene (17249-80-8) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → C18H43ClO4SSi6

Conditions	Yield
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 2,4,7-trimethyl-1,10-phenanthroline In tetrahydrofuran; cyclohexane at 80℃; for 24h; Inert atmosphere; Glovebox; regioselective reaction;	99%

1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + isopropenylbenzene (98-83-9) → 1,1,1,3,5,5,5-heptamethyl-3-(2-phenylpropyl)trisiloxane

Conditions	Yield
With cobalt pivalate; 1-adamantanecarbonitrile In neat (no solvent) at 80℃; for 24h;	99%
With C40H72Co2N8 In neat (no solvent) at 50℃; for 24h;	99%
With cobalt pivalate; 1-adamantanecarbonitrile In neat (no solvent) at 80℃; for 3h; Reagent/catalyst;	99 %Spectr.
With (π-Me5C5)Si+B(C6F5)4- In dichloromethane-d2 at 25℃; for 23h; Solvent; Inert atmosphere;	> 98 %Chromat.
With chloroplatinic acid 1,1,3,3-tetramethyl-1,3-divinyldisiloxane complex In isopropyl alcohol at 80 - 100℃; for 3h;

para-fluorostyrene (405-99-2) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → 1,1,1-3-5,5,5-heptamethyl-3-(2-(4-fluorophenyl)propyl)trisiloxane

Conditions	Yield
With cobalt pivalate; 1-adamantanecarbonitrile In neat (no solvent) at 80℃; for 24h;	99%

1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + 1,3-Dichlorobenzene (541-73-1) → 1,1,1,3,5,5,5-heptamethyl-3-(3,5-dichlorophenyl)trisiloxane

Conditions	Yield
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 2.9-dimethyl-1,10-phenanthroline In 1,4-dioxane at 100℃; for 6h; Catalytic behavior; Reagent/catalyst; Inert atmosphere; Sealed tube; regioselective reaction;	99%
With IrH3{κ3-P,O,P-[9,9-dimethyl-4,5-bis(diisopropylphosphino)xanthene]} In cyclohexene at 110℃; for 18h; Inert atmosphere; Glovebox;	94%
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 2,4,7-trimethyl-1,10-phenanthroline In tetrahydrofuran at 120℃; for 40h; Inert atmosphere; Sealed tube;	66%

1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + 4,4,5,5-tetramethyl-2-thiophen-3-yl-[1,3,2]dioxaborolane (214360-70-0) → C17H35BO4SSi3

Conditions	Yield
Stage #1: 1,1,1,3,5,5,5-heptamethyltrisiloxan With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; C25H35N3; cyclohexene In tetrahydrofuran Inert atmosphere; Glovebox; Stage #2: 4,4,5,5-tetramethyl-2-thiophen-3-yl-[1,3,2]dioxaborolane In tetrahydrofuran at 65℃; for 26h; Reagent/catalyst; Sealed tube; Inert atmosphere; regioselective reaction;	99%

styrene (292638-84-7) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → 1,1,1,3,5,5,5-heptamethyl-3-phenethyltrisiloxane (3439-16-5)

Conditions	Yield
With 1,3-bis(tert-buthylethynyl)-1,1,3,3-tetramethyldisiloxane platinum (0) at 100℃; for 24h; Reagent/catalyst;	98%
With 2,6-bis(1-(2,6-dimethylphenylimino)ethyl)pyridine; bis(cyclooctatetraene)(1-isocyanoadamantane)iron In neat (no solvent) at 80℃; for 23h; Reagent/catalyst;	92%
With bromopentacarbonylmanganese(I) In hexane at 20℃; for 4h; Schlenk technique; Inert atmosphere; Sealed tube; regioselective reaction;	90%

1-Heptene (592-76-7) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → 3-heptyl-1,1,1,3,5,5,5-heptamethyltrisiloxane (14579-46-5)

Conditions	Yield
With 1,2,3-trimethylimidazolium methylsulphate; bis(cyclooctadiene (μ-silyloxytrimethyl) rhodium(I)) at 90℃; for 2h; Product distribution; Further Variations:; Catalysts; Reagents;	98%
With C77H70N2OPtSi2 In toluene at 80℃; for 24h; Catalytic behavior; Reagent/catalyst; Inert atmosphere; Schlenk technique; regioselective reaction;	95%
dihydrogen hexachloroplatinate In isopropyl alcohol Heating;
(1,5-cyclooctadiene)rhodium/Aerosil 200 at 100℃; for 1h;	98 % Chromat.

1,2-Epoxy-4-vinylcyclohexane (106-86-5) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → 3-(2-(7-oxabicyclo[4.1.0]heptan-3-yl)ethyl)-1,1,1,3,5,5,5-heptamethyltrisiloxane

Conditions	Yield
With graphene nanoplates-supported platinum nanoparticles In neat (no solvent) at 80℃; for 2h; Catalytic behavior;	98%
With dihydrogen hexachloroplatinate at 75 - 85℃; for 2h;	96%
With dihydrogen hexachloroplatinate at 75 - 85℃;	96%

tetraethoxy orthosilicate (78-10-4) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → ethoxytris(1,1,1,3,5,5,5-heptamethyltrisilyloxy)silane

Conditions	Yield
With tris(pentafluorophenyl)-borane In hexane; toluene at 60℃; for 0.5h;	98%

p-fluorotoluene (352-32-9) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → C14H27FO2Si3 (1583285-93-1)

Conditions	Yield
With [Rh(coe)2OH]2; 3,4,5-MeO-MeO-BIPHEP; cyclohexene In tetrahydrofuran at 45℃; regioselective reaction;	98%

1,2-epoxy-5-hexene (10353-53-4) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → 1,1,1,3,5,5,5-heptamethyl-3-(4-(oxiran-2-yl)butyl)trisiloxane

Conditions	Yield
With [Rh(OH)cod]2 and diethylaminopropyltrimethoxysilane immobilized on SiO2 In neat (no solvent) at 40℃; for 2h;	98%

4-bromo-1-ethynylbenzene (766-96-1) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → 3-[(1Z)-2-(4-bromophenyl)ethenyl]-1,1,1,3,5,5,5-heptamethyltrisiloxane

Conditions	Yield
With [RuCl(CO)H(PCy3)2(1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene)] In dichloromethane at 20℃; for 1h; Inert atmosphere; Schlenk technique; diastereoselective reaction;	98%

1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + 1-vinyl-7-oxabicyclo<4.1.0>heptane (53601-12-0) → C15H32O3Si3

Conditions	Yield
With Pt-GPN (Pt on graphene nanoplatelet) In neat (no solvent) at 60℃; for 2h;	98%

1-bromo-3-chlorobenzene (108-37-2) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → 3-(3-bromo-5-chlorophenyl)-1,1,1,3,5,5,5-heptamethyltrisiloxane

Conditions	Yield
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 2.9-dimethyl-1,10-phenanthroline In 1,4-dioxane at 100℃; for 24h; Catalytic behavior; Reagent/catalyst; Inert atmosphere; Sealed tube; regioselective reaction;	98%

1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + 3-furylboronic acid pinacol ester (248924-59-6) → C17H35BO5Si3

Conditions	Yield
Stage #1: 1,1,1,3,5,5,5-heptamethyltrisiloxan With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; C25H35N3; cyclohexene In tetrahydrofuran Inert atmosphere; Glovebox; Stage #2: 3-furylboronic acid pinacol ester In tetrahydrofuran at 80℃; for 20h; Reagent/catalyst; Sealed tube; Inert atmosphere; regioselective reaction;	98%

1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + [5,15-di-n-butyl-10-ethoxycarbonylmethylporphyrinato]zinc(II) → [5,15-di-n-butyl-10-ethoxycarbonylmethyl-2-(1,1,1,3,5,5,5-heptamethyltrisiloxan-3-yl)porphyrinato]zinc(II)

Conditions	Yield
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine In 1,4-dioxane at 95℃; for 24h; Inert atmosphere;	98%

Allyl glycidyl ether (106-92-3) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → 1,1,1,3,5,5,5-heptamethyl-3-(3-(oxiran-2-ylmethoxy)propyl)trisiloxane (7422-52-8)

Conditions	Yield
With bis(1-butyl-4-methylpyridinium) hexachloroplatinate(IV) Reagent/catalyst;	97%
With C24H58OPtSi7 In benzene-d6; toluene at 50℃; for 5h; Reagent/catalyst; Schlenk technique;	95%
With cobalt nanoparticles In toluene for 7h; Inert atmosphere; UV-irradiation; Glovebox; Darkness;	95%

1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + 2,2,9,9-tetramethyl-3,8-dioxa-2,9-disiladec-5-yne (53326-60-6) → (1,4)-bis(trimethylsiloxy)-3-but-2-ene (128851-10-5)

Conditions	Yield
With dihydrogen hexachloroplatinate at 120℃; for 5h;	97%
With dihydrogen hexachloroplatinate In isopropyl alcohol at 125 - 140℃;
With platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex In toluene at 100℃; for 6h; Green chemistry;

pent-1-yn-5-ol (5390-04-5) + 1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) → (E)-5-(bis(trimethylsilyloxy)(methyl)silyl)-4-penten-1-ol (1032732-24-3)

Conditions	Yield
N-heterocyclic carbene-based platinum(0) complex In toluene at 60℃; for 0.2h;	97%

Upstream product

• 1438-82-0 1,1,1,3,3-pentamethyl-1,3-disiloxane 
• 75-54-7 Dichloromethylsilane 
• 1066-40-6 Trimethylsilanol 
• 992-94-9 methylsilane 
• 107-46-0 Hexamethyldisiloxane 
• 110-54-3 hexane 
• 99532-16-8 bis(trimethylsiloxy)(trimethylsilyl)methylsilane 
• 18027-10-6 sodium trimethylsilanolate 
• 75-77-4 chloro-trimethyl-silane 
• 6166-86-5 1,3,5,7,9-pentamethylcyclopentasiloxane 

Downstream Products

• 22407-46-1 3-chloro-1,1,1,3,5,5,5-heptamethyltrisiloxane 
• 7087-20-9 3-propenyl-1,1,1,3,5,5,5-heptamethyltrisiloxane 
• 17988-66-8 γ-chloropropyl(di(trimethylsiloxy))methylsilane 
• 920741-92-0 3-(DL-tocopheroloxypropyl)heptamethyltrisiloxane 
• 1072942-76-7 3-(2H-1,2,3-benzotriazol-2-yl)-5-(2-methyl-3-{1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl}-propyl)-4-biphenylol 
• 57222-10-3 α-Methyl-α--toluol 
• 3439-16-5 1,1,1,3,5,5,5-heptamethyl-3-phenethyltrisiloxane 
• 1361237-41-3 1,1,1,3,5,5,5-heptamethyl-3-(3-((tetrahydrofuran-2-yl)methoxy)propyl)trisiloxane 
• 194482-45-6 C₁₆H₃₂O₃Si₃ 
• 944152-65-2 C₂₅H₄₂O₄Si₃ 
• 1033596-98-3 C₂₈H₄₈O₄Si₃ 
• 1033596-96-1 C₂₈H₄₆O₄Si₃ 
• 1033596-91-6 C₃₅H₆₈O₆Si₆ 
• 1033596-93-8 C₃₅H₆₆O₆Si₆ 

Relevant articles and documents

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Method for preparing 1, 1, 1, 3, 5, 5, 5-heptamethyltrisiloxane

The invention discloses a method for preparing 1, 1, 1, 3, 5, 5, 5-heptamethyltrisiloxane. According to the method, concentrated sulfuric acid with the mass concentration being 98% serves as a catalyst, methyl hydrogen silicone oil 202 and hexamethyldisiloxane serve as raw materials, a catalyst reaction is conducted, and the 1, 1, 1, 3, 5, 5, 5-heptamethyltrisiloxane with the mass concentration being 99% and above is obtained. According to the method, the concentrated sulfuric acid serves as the catalyst, the catalyst is simple and easy to obtain, the price is low, the catalysis effect is good, operation is convenient and fast, production cost is lowered, and production efficiency is effectively improved.

Kinetic Investigation of the Platinum-catalysed Hydrosilylation of Vinylsiloxanes with Hydrogensiloxanes

A kinetic investigation of the platinum-catalysed hydrosilylation of monofunctional oligomeric vinylsiloxanes by monofunctional oligomeric hydrogensiloxanes was performed under stoichiometric conditions with use of quantitative 1H-NMR spectrometry.The reaction rate up to 50percent conversion can be expressed by v=k .During further hydrosilylation the kinetic changed to second order.No induction period was observed.A hydrogensiloxane with a dimethylsilyl end group gives much higher rates than a siloxane with a methylsiloxy group.The main reactions of all hydrosilylations, determined by GC-MS and 29Si-NMR, are β-additions.Less then 5percent α-products are obtained.