7790-99-0Relevant articles and documents
Near threshold photofragmentation dynamics of ICl-Ne A state van der Waals complexes
Drobits, Janet C.,Lester, Marsha I.
, p. 120 - 128 (1988)
The nascent ICl product state distribution is examined following vibrational predissociation of ICl-Ne A(νA=23) complexes via an optical-optical double resonance technique.ICl fragments are produced in approximately equal proportion in the νA=22 and 21 levels of the A(3Π1) state.Low rotational levels of ICl A(νA=22) are primarily populated, JA=1-8, accesing only a small portion of allowed states.ICl A(νA=21) fragments are produced with up to 69 cm-1 of rotational energy in a broad distribution which extends to nearly the energetic limit.Homogeneous broadening of the ICl-Ne feature indicates a vibrational predissociation lifetime between 2.3 and 50 ps.
I(2P1/2) Deactivation by ICl and Cl2
Lilenfeld, H. V.,Whitefield, P. D.,Bradburn, G. R.
, p. 6158 - 6162 (1984)
The rates of deactivation of I(2P1/2) by ICl and Cl2 have been measured in a fast-flow apparatus.The rate constant obtained for deactivation by ICl is fast (k = 1.5E-11 cm3 molecule-1 s-1) and is in good agreement with previous determinations by other workers.The rate constant obtained for deactivation by Cl2, however, is much slower (k = 1.7E-14 cm3 molecule-1 s-1) and is in contrast to earlier determinations by other workers, using static bulb techniques, who report much faster rates.Possible reasons for the discrepancy are advanced, and a possible mechanism to account for the fast deactivation by ICl is suggested.
Preparation method of hexafluorobutadiene
-
Paragraph 0039; 0045-0046; 0052; 0057-0059; 0064; 0069-0071, (2021/01/29)
The invention relates to a preparation method of hexafluorobutadiene, and belongs to the technical field of fluorine-containing gas preparation. The preparation method comprises the following steps: preparing a polar base solution, activated zinc and 1,2-dichloro2iodo-1,1,2-trifluoroethane, further preparing 1,2,3,4-tetrachlorohexafluorobutane, and finally preparing hexafluorobutadiene. Accordingto the method, activated zinc is used in the preparation process and is matched with a polar base solution serving as a solvent, so that the reaction rate is increased, the yield and selectivity of 1,2,3,4-tetrachlorohexafluorobutane are guaranteed; therefore, the problem that the reaction rate is influenced by using zinc particles which are not activated and have larger particles and adopting a solvent with poorer polarity in the prior art is solved; in addition, a non-polar solvent and activated zinc are added in the preparation of hexafluorobutadiene, so that byproducts generated in the preparation process of hexafluorobutadiene are easier to separate while the yield and selectivity of hexafluorobutadiene are ensured.
Method for preparing hexafluorobutadiene from iodine and chlorine
-
Paragraph 0034-0035; 0045-0046; 0056-0057, (2017/08/27)
The invention relates to a method for preparing hexafluorobutadiene from iodine and chlorine. The method comprises the following steps: preparing a metal coordinated ionic liquid solvent, and reacting iodine with chlorine to prepare iodine monochloride; reacting iodine monochloride with chlorotrifluoroethylene in the presence of the metal coordinated ionic liquid solvent to prepare 1,2-dichloro-2-iodo-1,1,2-trifluoroethane; carrying out a reaction on the 1,2-dichloro-2-iodo-1,1,2-trifluoroethane in the presence of the metal coordinated ionic liquid solvent under the catalysis of zinc powder to obtain 1,2,3,4-tetrachloro-1,1,2,3,4,4-hexafluorobutane; and reacting the 1,2,3,4-tetrachloro-1,1,2,3,4,4-hexafluorobutane with zinc powder in the presence of the metal coordinated ionic liquid solvent to generate hexafluorobutadiene.
Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
-
Paragraph 1083; 1084; 1085; 1086, (2013/03/26)
The present invention relates to compounds defined by formula I wherein the variables R1-R8 are defined as in the description, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of cholesterol ester transfer protein (CETP) and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme.
Stabilizing aqueous solution of iodine chloride by adding sodium chloride
-
Page/Page column 3, (2011/02/19)
This invention relates generally to non-ionic X-ray contrast agents. It further relates to the preparation of iodine chloride, a key reagent in the synthesis of non-ionic X-ray contrast agents such as iodixanol and iohexol. In particular, the iodine chloride is produced in a reaction involving iodine, sodium chlorate, and hydrochloric acid as the starting materials. The instant invention relates to a method of stabilizing aqueous iodine chloride solutions by adding about one to about four molar equivalents of sodium chloride relative to sodium chlorate to an aqueous reaction mixture of sodium chlorate, hydrochloric acid, and iodine.
Obtaining free iodine in preparation of aqueous iodine chloride by adding potassium iodide
-
Page/Page column 4, (2011/02/19)
This invention relates generally to the preparation of non-ionic X-ray contrast agents, iohexol, ioversol, and iodixanol. It further relates to an improved method for the iodination reaction, a key step in the industrial preparation of non-ionic X-ray contrast agents. In particular, it relates to a method for producing free iodine in an aqueous solution of iodine chloride by adding minor amounts of potassium iodide.
Design and synthesis of nonpeptidic, small molecule inhibitors for the Mycobacterium tuberculosis protein tyrosine phosphatase PtpB
Rawls, Katherine A.,Grundner, Christoph,Ellman, Jonathan A.
, p. 4066 - 4070 (2010/10/05)
The design and synthesis of new inhibitor analogues for the Mycobacterium tuberculosis (Mtb) phosphatase PtpB is described. Analogues were synthesized by incorporation of two common and effective phosphate mimetics, the isothiazolidinone (IZD) and the difluoromethylphosphonic acid (DFMP). The basic scaffold of the inhibitor was identified from structure-activity relationships established for a previously published isoxazole inhibitor, while the phosphate mimetics were chosen based on their proven cell permeability and activity when incorporated into previously reported inhibitors for the phosphatase PTP1B. The inhibitory activity of each compound was evaluated, and each was found to have low or submicromolar affinity for PtpB.
Ion-detecting sensors comprising plasticizer-free copolymers
-
, (2008/06/13)
Ion-detecting sensors for detecting a target ion in a sample are provided. The sensor comprises a plasticizer-free copolymer comprised of polymerized units of methacrylate monomers having pendent alkyl groups of different length and a functionalized ionophore of said ion, wherein at least a portion of the functionalized ionophore is grafted into the copolymer through covalent linkages. Sensors may comprise ionophores such as hydrophilic crown ethers or functionalized derivative of 3-oxapentandiaminde-type ionophores. This invention further provides sensors for detecting target ions in a sample, comprising plasticizer-free molecularly imprinted polymers, wherein the polymers comprise polymerized units of methacrylate monomers having pendent alkyl groups of different length and a functionalized ionophore of said ion. In particular, a magnesium ion sensor comprising a functionalized derivative of a 3-oxapentandiaminde-type calcium ion-selective ionophore is provided. Sensors of this invention include carrier-based ion-selective electrodes or optodes such as thin film ion-specific optodes, particle-based optodes, or bulk optodes.
A facile synthesis of 1,4-dialkoxy-2,5-diiodobenzenes: reaction of dialkoxybenzenes with iodine monochloride in alcoholic solvents
Wariishi, Koji,Morishima, Sin-Ichi,Inagaki, Yoshio
, p. 98 - 100 (2013/09/05)
A facile synthesis of 1,4-dialkoxy-2,5-diiodobenzenes via diiodination of the corresponding dialkoxybenzenes with iodine monochloride has been developed. Employment of ah alcoholic solvent as a reaction medium is crucial for attaining a high yield; the reaction in a nonalcoholic solvent usually resulted in a poor yield. The diiodobenzene derivatives are useful intermediates in the synthesis of such advanced materiais as soluble phenylenevinylene polymers anal dialkoxy derivatives of 7,7,8,8-tetracyanoquinodimethane.
