3395-91-3Relevant articles and documents
Synthesis of β-haloketones by β-addition reactions of α,β-unsaturated ketones with BX3 (X = Br, Cl) as halide source
Lee, Adam Shih-Yuan,Wang, Shu-Huei,Chang, Yu-Ting
, p. 364 - 368 (2014)
A series of β-bromoketones and β-chloroketones were synthesized by the addition reactions of α,β-unsaturated ketones under BX 3 (X = Br, Cl) and ethylene glycol reaction system. The α,β-unsaturated ester also was successfully converted to its corresponding β-bromoester under the reaction condition. A series of β-bromoketones and β-chloroketones were synthesized by the addition reactions of α,β-unsaturated ketones under BX3 (X=Br, Cl) and ethylene glycol reaction system. Copyright
Ligand-Enabled Pd(II)-Catalyzed Bromination and Iodination of C(sp3)-H Bonds
Zhu, Ru-Yi,Saint-Denis, Tyler G.,Shao, Ying,He, Jian,Sieber, Joshua D.,Senanayake, Chris H.,Yu, Jin-Quan
supporting information, p. 5724 - 5727 (2017/05/04)
We herein report the palladium(II)-catalyzed bromination and iodination of a variety of α-hydrogen-containing carboxylic acid and amino acid-derived amides. These reactions are exclusively enabled by quinoline-type ligands. The halogenated products obtained in this reaction are highly versatile and rapidly undergo further diversification. Further, we report the first example of a free carboxylic acid-directed Pd(II)-catalyzed C(sp3)-H bromination, enabled by quinoline ligands.
Synthesis of [3-13C]-, [4-13C]- and [11- 13C]-porphobilinogen
Dawadi, Prativa B. S.,Schulten, Els A. M.,Lugtenburg, Johan
experimental part, p. 341 - 349 (2011/07/08)
[4-13C]-porphobilinogen 1a, [3-13C]-porphobilinogen 1b and [11-13C]-porphobilinogen 1c are prepared from [1- 13C]-3-(tetrahydropyran-20-yloxy)-propionaldehyde 2a, methyl [4- 13C]-4-nitrobutyrate 3b and [1-13C]-isocyanoacetonitrile 5c, respectively. The building blocks 2, 3 and 5 can be prepared efficiently in any isotopomeric form. Via base-catalyzed condensation of these building blocks porphobilinogen can be enriched with 13C and 15N stable isotopes at any position and combination of positions. Copyright