77-76-9Relevant articles and documents
Pressure Stabilization and Solvation Thermodynamics of a Hemiketal Reaction Intermediate
Gift, Alan D.,Ben-Amotz, Dor
, p. 11459 - 11462 (2000)
This work reports the first pressure stabilization of a hemiketal intermediate, 2-methoxy-2 propanol, formed in the reaction of acetone and methanol, observed using Raman spectroscopy. Acetone dissolved in methanol is found to undergo a two-step reaction, with the ketal 2,2-dimethoxy-propane as the final product and the hemiketal observed as an intermediate. In a more dilute stoichiometric mixture of acetone and methanol in liquid tetrahydrofuran (THF), quantitative formation of the hemiketal is observed at pressures above 2 GPa. The complete set of reaction thermodynamic functions (ΔH0, ΔV0, ΔS0, ΔG0, ΔU0, ΔA0) is obtained for the hemiketal formation reaction in THF as a function of temperature and pressure and compared with previous measurements of ΔH0, ΔS0, and ΔG0 for acetone dissolved in methanol. Comparisons with quantum calculations for the isolated reactant and product species are used to completely quantitate the effects of solvation on the hemiketal formation reaction.
Preparation method of 2, 2-dimethoxypropane
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Paragraph 0026; 0027; 0028; 0029; 0030; 0031; 0032, (2019/01/24)
The invention discloses a preparation method of 2, 2-dimethoxypropane. The method adopts methanol and acetone as the raw materials, utilizes a metal oxide modified SO4/SnO2 catalyst to catalyze reaction, and includes the reaction steps of: a) subjecting methanol and acetone to preheating vaporization by a preheater respectively, and controlling the preheating temperature at 65-95DEG C; b) letting the vaporized methanol and acetone enter the reactor respectively, and contacting the vaporized methanol and acetone with the metal oxide modified SO4/SnO2 catalyst for catalytic reaction in the reactor at a temperature of 83-95DEG C so as to obtain a crude product containing 2, 2-dimethoxypropane and unreacted methanol and acetone. Specifically, the metal oxide is one of or a mixture of several of Fe2O3, Al2O3 and Ga2O3. The method adopted by the invention is carried out at high temperature, solves the problem of long reaction time at low temperature, has high single conversion rate,and does not introduce new impurities are introduced in the subsequent concentration process.
2,2-dimethoxypropane production method
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Paragraph 0024-0037, (2019/10/23)
The invention discloses a 2,2-dimethoxypropane production method. Methanol and acetone are used as raw materials, strong acid cation exchange resin serves as a catalyst, super absorbent resin serves as a dehydrating agent, and a product is obtained through reduced pressure rectification. The super absorbent resin can be recycled after hot air drying, and a mixture of a small quantity of methanol,acetone and 2,2-dimethoxypropane and water after drying can be separated through pressurized condensation, the separated water can be discharged directly, and the separated mixture of methanol, acetone and 2,2-dimethoxypropane are returned to a fixed bed reactor to continue to participate in reaction. The method is simple in process, high in continuity and low in cost, the total yield of productsis high and is greater than 65%, high quality is achieved while the purity is higher than 99%, and a high industrial application value is achieved.