93-61-8 Usage
Description
N-Methylformanilide, also known as N-methyl-o-toluidine, is an organic compound that serves as an important intermediate in the synthesis of various organic and organometallic compounds. It is characterized by its ability to act as a formylating agent and a swelling agent in specific applications.
Uses
Used in Organic Synthesis:
N-Methylformanilide is used as a formylating reagent for certain organometallics, playing a crucial role in the synthesis of complex organic molecules. Its reactivity and stability make it a valuable component in the formation of desired products.
Used in Vilsmeier-Haack Reactions:
In the field of organic chemistry, N-Methylformanilide is utilized in combination with phosphoryl chloride for Vilsmeier-Haack reactions. This reaction is an efficient method for the synthesis of formyl derivatives, which are essential building blocks in the preparation of various organic compounds.
Used in Heterocycle Syntheses:
N-Methylformanilide also finds application in the synthesis of heterocycles, which are compounds containing a ring structure with at least one heteroatom. Its ability to formylating agents makes it a useful component in the creation of these diverse and important classes of compounds.
Used in Textile Industry:
In the dyeing process of meta-aramid fibers, N-Methylformanilide acts as a swelling agent. This application is crucial for enhancing the dye uptake and improving the overall quality of the finished product, making it an essential component in the textile industry.
Flammability and Explosibility
Notclassified
Check Digit Verification of cas no
The CAS Registry Mumber 93-61-8 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 3 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 93-61:
(4*9)+(3*3)+(2*6)+(1*1)=58
58 % 10 = 8
So 93-61-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO/c1-9(7-10)8-5-3-2-4-6-8/h2-7H,1H3
93-61-8Relevant articles and documents
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Fieser,Jones
, p. 66 (1940)
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Unreactive C-N Bond Activation of Anilines via Photoinduced Aerobic Borylation
Ji, Shuohan,Luo, Lu,Qin, Shengxiang,Yin, Chunyu,Zhang, Hua
supporting information, (2021/12/27)
Unreactive C-N bond activation of anilines was achieved by photoinduced aerobic borylation. A diverse range of tertiary and secondary anilines were converted to aryl boronate esters in moderate to good yields with wide functional group tolerance under simple and ambient photochemical conditions. This transformation achieved the direct and facile C-N bond activation of unreactive anilines, providing a convenient and practical route transforming widely available anilines into useful aryl boronate esters.
Preparation and catalytic evaluation of a palladium catalyst deposited over modified clinoptilolite (Pd&at;MCP) for chemoselective N-formylation and N-acylation of amines
Amirsoleimani, Mina,Khalilzadeh, Mohammad A.,Zareyee, Daryoush
, (2020/08/22)
Novel palladium nanoparticles stabilized by clinoptilolite as a natural inexpensive zeolite prepared and used for N-formylation and N-acylation of amines at room temperature at environmentally benign reaction conditions in good to excellent yields. Pd (II) was immobilized on the surface of clinoptilolite via facile multi-step amine functionalization to obtain a sustainable, recoverable, and highly active nano-catalyst. The structural and morphological characterizations of the catalyst carried out using XRD, FT-IR, BET and TEM techniques. Moreover, the catalyst is easily recovered using simple filtration and reused for 7 consecutive runs without any loss in activity.