600-22-6Relevant articles and documents
The electron stimulated chemistry of methyl lactate on Cu(1 1 1)
Fleming,Kadodwala
, p. 409 - 414 (2010)
The electron stimulated chemistry of monolayers of (R)/(S)-methyl lactate ((S)/(R)-MLAc) adsorbed on Cu(1 1 1) has been investigated. Monolayers of MLAc undergo highly efficient electron stimulated processes predominately desorption, but also a significant fraction is converted to an adsorbed alkoxide moiety through the selective cleavage of the O-H bond. The efficiency of the depletion of the adsorbed MLAc state and the absence of significant non-selective fragmentation contrasts with previous studies of the electron beam irradiation of monolayers of oxygen containing organic molecules.
The Oxidation of Methacrylic Acid Esters with H2O2 in the Presence of Chromium Catalysts. A Novel Route to Pyruvic Acid Esters
Inoue, Masami,Uragaki, Toshitaka,Kashiwagi, Hiroshi,Enomoto, Saburo
, p. 99 - 100 (1989)
The oxidation of methacrylic acid esters to pyruvic acid esters was carried out with aqueous H2O2 in CH3CN in the presence of a catalytic amount of chromium compounds such as Cr(III)(acac)3, chromium salts, and chromic acid.The oxidation of methyl methacrylate in the presence of chromic acid and triethylamine (1:1) gave an 82 percent conversion with a 72 percent selectivity to methyl pyruvate at 40 deg C for 20 h.
Metal-Free Synthesis of Polysubstituted Imidazolinone Through Cyclization of Amidines with 2-Substituted Acrylates
Liu, Zhen,Zhang, Yan-Shun,Wei, Yin,Shi, Min
supporting information, p. 1093 - 1099 (2020/02/27)
Polysubstituted imidazolinones were synthesized in a facile metal-free cascade nucleophilic cyclization of easily available amidines and 2-substituted acrylates. This protocol is distinguished by simple, mild, and catalyst-free reaction conditions with a broad substrate scope, affording the desired products in moderate to good yields and providing an efficient strategy for synthesis of polysubstituted imidazolinone.
Conversion of Dihydroxyacetone to Methyl Pyruvate Catalyzed by Hybrid Molecular Sieves at Low Temperature: A Strategy for the Green Utilization of Glycerol
Luo, Qianqian,Lu, Tianliang,Xu, Jun,Yang, Xiaomei,Zhou, Lipeng
, p. 1641 - 1649 (2019/12/24)
Abstract: Methyl pyruvate (MPA) was synthesized from dihydroxyacetone (DHA), the oxidation product of glycerol, over Sn-β and TS-1 hybrid molecular sieves at low temperature. Sn-β and TS-1 provide the active sites for conversion of DHA to methyl lactate (MLA) and oxidation of MLA to MPA, respectively. Synergism of Lewis acid sites on Sn-β and TS-1 realize the production of MPA from DHA. After optimization, 71% yield of MPA can be obtained under 50?°C. This is the first report for the synthesis of MPA from DHA directly. Graphic Abstract: [Figure not available: see fulltext.].
Novel synthesis method of alpha-carbonyl acid ester
-
Paragraph 0016; 0050; 0054-0055, (2020/07/21)
The invention discloses a novel synthesis method of alpha-carbonyl acid ester. The method comprises the following steps: carrying out chlorination reaction on an alpha-methylene-containing nitrile compound and chlorine to obtain dichloronitrile, reacting the dichloronitrile product in a sulfuric acid and water system to obtain formyl cyanide, then acquiring an imino sulfate compound in the same reaction system, and finally performing esterification to obtain the target product. The adopted reaction raw materials are wide in sources and low in price, highly toxic solid sodium cyanide can be prevented from being used in the prior art, the method is environmentally friendly, and the method is easy to operate, mild in condition and easy to industrialize.
Novel effect of zinc nitrate/vanadyl oxalate for selective catalytic oxidation of α-hydroxy esters to α-keto esters with molecular oxygen: An in situ ATR-IR study
Ju, Yongwei,Du, Zhongtian,Xiao, Chuhong,Li, Xingfei,Li, Shuang
supporting information, (2019/04/05)
Selective oxidation of α-hydroxy esters is one of the most important methods to prepare high value-added α-keto esters. An efficient catalytic system consisting of Zn(NO3)2/VOC2O4 is reported for catalytic oxidation of α-hydroxy esters with molecular oxygen. Up to 99% conversion of methyl DL-mandelate or methyl lactate could be facilely obtained with high selectivity for its corresponding α-keto ester under mild reaction conditions. Zn(NO3)2 exhibited higher catalytic activity in combination with VOC2O4 compared with Fe(NO3)3 and different nitric oxidative gases were detected by situ attenuated total reflection infrared (ATR-IR) spectroscopy. UV-vis and ATR-IR results indicated that coordination complex formed in Zn(NO3)2 in CH3CN solution was quite different from Fe(NO3)3; it is proposed that the charge-transfer from Zn2+ to coordinated nitrate groups might account for the generation of different nitric oxidative gases. The XPS result indicate that nitric oxidative gas derived from the interaction of Zn(NO3)2 with VOC2O4 could be in favor of oxidizing VOC2O4 to generate active vanadium (V) species. It might account for different catalytic activity of Zn(NO3)2 or Fe(NO3)3 combined with VOC2O4. This work contributes to further development of efficient aerobic oxidation under mild reaction conditions.
Method for preparing keto ester by catalytic oxidation of hydroxy ester (by machine translation)
-
Paragraph 0024; 0025; 0026; 0027; 0028; 0029; 0030-0050, (2019/10/01)
The invention relates to a method, in particular to a method for preparing ketoester by catalytic oxidation of hydroxy ester. Belong to high added value's fine chemicals technical field. The method uses molecular oxygen as an oxygen source, uses a vanadium-based nitrogen-doped carbon material as a catalyst, and selectively oxidizes hydroxyl ester to a ketone ester in a liquid phase solvent, and specifically is: a catalyst, α - hydroxyl ester, a liquid phase 40 - 180 °C reaction solvent are put into a high-pressure reactor, oxygen source, closed reaction kettle, stirring, heating and temperature raising . reaction time 0 - 12h obtains a product. Compared with a traditional pyruvic acid esterification method and the like, the invention, compared with the traditional pyruvic acid esterification method and the like. The method is mild in reaction condition, high, the conversion rate of the raw materials and the product selectivity are high, and the method has important application prospects. (by machine translation)
Base-free conversion of glycerol to methyl lactate using a multifunctional catalytic system consisting of Au-Pd nanoparticles on carbon nanotubes and Sn-MCM-41-XS
Tang, Zhenchen,Boer, Dina G.,Syariati, Ali,Enache, Mihaela,Rudolf, Petra,Heeres, Hero J.,Pescarmona, Paolo P.
, p. 4115 - 4126 (2019/08/12)
Multifunctional catalytic systems consisting of physical mixtures of (i) bimetallic Au-Pd nanoparticles (average size of 3-5 nm) supported on functionalised carbon nanotubes (CNTs) and (ii) Sn-MCM-41 nanoparticles (50-120 nm), were synthesised and investigated for the base-free, selective conversion of glycerol to methyl lactate in a batch reactor. The catalysts were characterised by means of transmission electron microscopy, N2-physisorption, energy-dispersive X-ray spectroscopy, X-ray photoelectron spectroscopy and by Boehm titration. The catalyst based on bimetallic AuPd/CNTs showed much higher activity than the monometallic Au or Pd counterparts, thus indicating synergetic effects. Functionalisation of the CNTs by oxidative treatments had a positive effect on catalyst performance, which was correlated to the observed increase in surface acidity and hydrophilicity. The highest yield of methyl lactate achieved in this work was 85% at 96% glycerol conversion (140 °C, 10 h at 30 bar air), which is the highest yield ever reported in the literature so far. Insights in the reaction pathway were obtained by monitoring the conversion-time profiles for intermediates and their possible role as inhibitors. Batch recycling experiments demonstrated the excellent reusability of the catalyst.
Green synthesizing process for pyruvate
-
Paragraph 0031; 0032; 0033, (2018/04/27)
The invention provides a green synthesizing process for pyruvate. Multi-phase catalysis reaction is adopted, a catalyst can be recycled, moreover, catalysis reaction does not need a solvent, reactionconditions are mild, produced wastes are less, and energy conservation and environmental protection are achieved.
Method for preparing pyruvate through liquid-phase catalytic oxidation of lactate
-
Paragraph 0030-0035; 0037-0078, (2018/12/13)
The invention provides a method for preparing pyruvate through liquid-phase catalytic oxidation of lactate. The method comprises the following steps: mixing the lactate, a compound catalyst, an oxidant and a reaction solvent and putting a mixture into a reaction container; after mounting the reaction container, starting cooling water and condensing and refluxing, wherein the compound catalyst comprises metal halide and a solid acid catalyst; stirring and raising the temperature to reaction temperature; reacting for certain time at constant temperature; decompressing and distilling to remove the reaction solvent; washing with water to remove an inorganic catalyst; extracting a product by utilizing dichloromethane; decompressing and distilling to remove the dichloromethane to obtain a product, i.e., the lactate. Compared with synthesis methods including a tartrate hydrolysis method, a pyruvate esterification method and the like, the method has the advantages of few reaction steps, moderate reaction conditions, green and environment-friendly reaction process, cheap and efficient catalyst and relatively high conversion rate of raw materials and product selectivity; the method has a relatively good application prospect and relatively high practical value.
